Olanzapine and Glucotrol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Olanzapine (olanzapine) and Glucotrol (glipizide). Common drug interactions include chest pain among females and hypertension among males.
The phase IV clinical study analyzes what interactions people have when they take Olanzapine and Glucotrol. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Olanzapine?
Olanzapine has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 69,242 Olanzapine users. Check the latest studies of Olanzapine.
What is Glucotrol?
Glucotrol has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 20,322 Glucotrol users. Check the latest studies of Glucotrol.
23 people who take Olanzapine and Glucotrol together, and have interactions are studied.

What are the common drug interactions of Olanzapine and Glucotrol, by gender? *:
female:
- Chest pain
- Blood cholesterol increased
- Blood triglycerides increased
- Ankle fracture
- Blood disorder
- Blood glucose decreased
- Blood glucose increased
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Delirium (wild excitement)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
male:
- Hypertension (high blood pressure)
- Pain
- Neuropathy peripheral (surface nerve damage)
- Paralysis
- Platelet count decreased
- Proteinuria (presence of protein in the urine)
- Renal failure (kidney dysfunction)
- Ageusia (loss of taste functions of the tongue)
- Cardiac failure congestive
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
What are the common drug interactions of Olanzapine and Glucotrol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Cardiac failure congestive
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Depressed level of consciousness
- Electrocardiogram st segment depression
- Electrocardiogram t wave peaked
- Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Overdose
20-29:
n/a
30-39:
- Appetite disorder (abnormal eating habits)
- Dysgeusia (disorder of the sense of taste)
- Hyperglycaemia (high blood sugar)
- Nausea (feeling of having an urge to vomit)
- Neuropathy peripheral (surface nerve damage)
- Platelet count decreased
- Ageusia (loss of taste functions of the tongue)
- Decreased appetite
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
40-49:
- Chest pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
- Emotional distress
- Hypertension (high blood pressure)
- Pain
- Renal failure (kidney dysfunction)
- Ankle fracture
- Blood glucose decreased
50-59:
- Tardive dyskinesia (a disorder that involves involuntary movements)
- Cardiac failure
- Heart rate decreased
- Suicidal behaviour
- Suicidal ideation
60+:
- Blood cholesterol increased
- Blood triglycerides increased
- Blood glucose increased
- Dyspnoea (difficult or laboured respiration)
- Glycosylated haemoglobin increased
- Red blood cell count decreased
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 4 people, 17.39%
- Wheezing (a high-pitched whistling sound made while you breath): 2 people, 8.70%
- Rickets (softening of bones): 2 people, 8.70%
- Plasmacytoma (neoplasm of plasma cells (usually in bone marrow)): 2 people, 8.70%
- Pain: 2 people, 8.70%
- Hiv Infection: 2 people, 8.70%
- Depression: 2 people, 8.70%
- Constipation: 2 people, 8.70%
- Back Pain: 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Olanzapine and Glucotrol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Olanzapine (69,242 reports)
- Glucotrol (20,322 reports)
Browse all drug interactions of Olanzapine and Glucotrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Olanzapine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Glucotrol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Olanzapine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glucotrol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
- Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on olanzapine and glipizide (the active ingredients of Olanzapine and Glucotrol, respectively), and Olanzapine and Glucotrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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