Oncaspar and Bactrim ds drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oncaspar (pegaspargase) and Bactrim ds (sulfamethoxazole; trimethoprim). Common drug interactions include anaphylactic reaction among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Oncaspar and Bactrim ds. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Oncaspar?

Oncaspar has active ingredients of pegaspargase. eHealthMe is studying from 5,504 Oncaspar users. Check the latest studies of Oncaspar.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

On Jul, 13, 2026

13 people who take Oncaspar and Bactrim ds together, and have interactions are studied.

Oncaspar and Bactrim ds drug interactions.

What are the common drug interactions of Oncaspar and Bactrim Ds, by gender? *:

female:

Anaphylactic reaction (serious allergic reaction)
Confusion
Dyspnoea (difficult or laboured respiration)
Gait abnormal
Hyperlipidaemia (presence of excess lipids in the blood)
Hypotension (abnormally low blood pressure)
Loss of consciousness
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Sedation

male:

Abdominal pain
Arthralgia (joint pain)
Alanine aminotransferase increased
Anaphylactic reaction (serious allergic reaction)
Antithrombin iii deficiency (rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism, and repetitive intrauterine fetal death (iufd))
Back pain
Blood fibrinogen decreased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chills (felling of cold)
Dyspnoea exertional (breathlessness or shortness of breath)

What are the common drug interactions of Oncaspar and Bactrim Ds, by age (0-1 to 60+)? *:

0-1:

Subclavian artery thrombosis (a condition in which the blood flow through the vessel is obstructed)

2-9:

Hyperlipidaemia (presence of excess lipids in the blood)
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)

10-19:

Enterococcal infection
Wound dehiscence (a surgical incision reopens either internally or externally)
Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Acinetobacter test positive
Anaphylactic reaction (serious allergic reaction)
Antithrombin iii deficiency (rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism, and repetitive intrauterine fetal death (iufd))
Dyspnoea (difficult or laboured respiration)
Embolic stroke (stroke due to obstruction due to an embolus)
Fall
Hypotension (abnormally low blood pressure)

20-29:

Abdominal pain upper
Alanine aminotransferase increased
Anaphylactic reaction (serious allergic reaction)
Back pain
Blood fibrinogen decreased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chills (felling of cold)
Dyspnoea exertional (breathlessness or shortness of breath)
Epistaxis (bleed from the nose)
Headache (pain in head)

30-39:

Confusion
Gait abnormal
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Sedation

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 38.46%
Precursor B-Lymphoblastic Lymphoma (precursor b-cell cancer): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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