Ondansetron and Dotarem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ondansetron (ondansetron) and Dotarem (gadoterate meglumine). Common drug interactions include cytokine release syndrome among females and abscess limb among males.

The phase IV clinical study analyzes what interactions people have when they take Ondansetron and Dotarem. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.

What is Dotarem?

Dotarem has active ingredients of gadoterate meglumine. eHealthMe is studying from 2,749 Dotarem users. Check the latest studies of Dotarem.



On Jul, 28, 2026

19 people who take Ondansetron and Dotarem together, and have interactions are studied.

Ondansetron and Dotarem drug interactions.

What are the common drug interactions of Ondansetron and Dotarem, by gender? *:

female:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Dysarthria (speech disorder)
  3. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Bone pain
  6. Herpes zoster
  7. Wound infection
  8. Acute respiratory failure
  9. Anaphylactic reaction (serious allergic reaction)

male:

  1. Abscess limb (limb infection)
  2. Injection site extravasation (flow of (blood or lymph) from injection site)
  3. Pain in extremity
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the common drug interactions of Ondansetron and Dotarem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Dysarthria (speech disorder)

10-19:

  1. Bone pain
  2. Herpes zoster

20-29:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

30-39:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

  1. Injection site extravasation (flow of (blood or lymph) from injection site)
  2. Pain in extremity

50-59:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

60+:

  1. Wound infection
  2. Abscess limb (limb infection)
  3. Acute respiratory failure
  4. Anaphylactic reaction (serious allergic reaction)

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 10 people, 52.63%
  2. Constipation: 10 people, 52.63%
  3. Stress And Anxiety: 10 people, 52.63%
  4. Nausea And Vomiting: 10 people, 52.63%
  5. Oral Herpes (viral infection of mouth): 9 people, 47.37%
  6. Birth Control: 9 people, 47.37%
  7. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 9 people, 47.37%
  8. Pain In Extremity: 9 people, 47.37%
  9. Pain: 2 people, 10.53%
  10. Bone Marrow Conditioning Regimen: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Ondansetron and Dotarem?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ondansetron and Dotarem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ondansetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dotarem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ondansetron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dotarem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron and gadoterate meglumine (the active ingredients of Ondansetron and Dotarem, respectively), and Ondansetron and Dotarem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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