Ondansetron and Firdapse drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ondansetron (ondansetron) and Firdapse (amifampridine). Common drug interactions include bronchitis among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Ondansetron and Firdapse. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,739 Ondansetron users. Check the latest studies of Ondansetron.

What is Firdapse?

Firdapse has active ingredients of amifampridine. eHealthMe is studying from 2,112 Firdapse users. Check the latest studies of Firdapse.

On Aug, 11, 2026

69 people who take Ondansetron and Firdapse together, and have interactions are studied.

Ondansetron and Firdapse drug interactions.

What are the common drug interactions of Ondansetron and Firdapse, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dehydration (dryness resulting from the removal of water)
Pneumonia
Abdominal discomfort
Contusion (a type of hematoma of tissue in which capillaries)
Hospitalisation
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Rash
Small cell lung cancer extensive stage (small cell lung cancer that has spread (metastasized) to other regions of the body such as another lobe of the lung or the brain)
Small cell lung cancer metastatic (lung cancer spreads to other body parts)

male:

Asthenia (weakness)
Fall
Haemoglobin decreased
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)
Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Respiratory failure (inadequate gas exchange by the respiratory system)
Rib fracture

What are the common drug interactions of Ondansetron and Firdapse, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Fall
Balance disorder
Contusion (a type of hematoma of tissue in which capillaries)
Impaired healing
Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)
Alopecia (absence of hair from areas of the body)
Infusion site pain
Infusion site swelling
Liver disorder (liver diseases)
Ocular icterus (presence of jaundice seen in the sclera of the eye)

40-49:

Abdominal pain upper
Body temperature increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Hyperhidrosis (abnormally increased sweating)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Blood glucose increased
Blood pressure increased
Diarrhoea
Feeling hot

50-59:

Bladder pain
Brain neoplasm (tumour of brain)
Colitis (inflammation of colon)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Cough
Hypertension (high blood pressure)
Urinary tract infection
Vision blurred
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Oral fungal infection

60+:

Fall
Asthenia (weakness)
Constipation
Dehydration (dryness resulting from the removal of water)
Blood pressure increased
Brain natriuretic peptide increased
Fibrin d dimer increased
Haemoglobin decreased
Headache (pain in head)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the existing conditions these people have? *

Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 65 people, 94.20%
High Blood Cholesterol: 5 people, 7.25%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 4 people, 5.80%
Lung Cancer - Small Cell (lung cancer): 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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