Onfi and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Onfi (clobazam) and Premarin (estrogens, conjugated). Common drug interactions include aura among females.

The phase IV clinical study analyzes what interactions people have when they take Onfi and Premarin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Onfi?

Onfi has active ingredients of clobazam. It is often used in epilepsy. eHealthMe is studying from 7,809 Onfi users. Check the latest studies of Onfi.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

12 people who take Onfi and Premarin together, and have interactions are studied.

What are the common drug interactions of Onfi and Premarin, by gender? *:

female:

Aura
Cerebral disorder (brain disease)
Hypotension (abnormally low blood pressure)
Intraductal papillary mucinous neoplasm (tumour (neoplasm) that grows within the pancreatic ducts)
Joint dislocation (a joint position is changed from normal position)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Rash
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Throat irritation

male:

n/a

What are the common drug interactions of Onfi and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Aura
Eye movement disorder

50-59:

n/a

60+:

Aura
Cerebral disorder (brain disease)
Hypotension (abnormally low blood pressure)
Intraductal papillary mucinous neoplasm (tumour (neoplasm) that grows within the pancreatic ducts)
Joint dislocation (a joint position is changed from normal position)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Rash
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Throat irritation

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 50.00%
Partial Seizures (seizures which affect only a part of the brain at onset): 5 people, 41.67%
Neuropathy Peripheral (surface nerve damage): 4 people, 33.33%
Depression: 4 people, 33.33%
Vasculitis (inflammation of a blood vessel or blood vessels): 3 people, 25.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 25.00%
Optic Neuritis (optic nerve inflammation): 3 people, 25.00%
High Blood Pressure: 3 people, 25.00%
Abdominal Discomfort: 3 people, 25.00%
Tonsillitis (inflammation of tonsil): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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