Onglyza and Silodosin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Onglyza (saxagliptin hydrochloride) and Silodosin (silodosin). Common drug interactions include pemphigoid among males.

The phase IV clinical study analyzes what interactions people have when they take Onglyza and Silodosin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Onglyza?

Onglyza has active ingredients of saxagliptin hydrochloride. It is often used in diabetes. eHealthMe is studying from 8,638 Onglyza users. Check the latest studies of Onglyza.

What is Silodosin?

Silodosin has active ingredients of silodosin. eHealthMe is studying from 3,839 Silodosin users. Check the latest studies of Silodosin.



On Jul, 05, 2026

12 people who take Onglyza and Silodosin together, and have interactions are studied.

Onglyza and Silodosin drug interactions.

What are the common drug interactions of Onglyza and Silodosin, by gender? *:

female:

n/a

male:

  1. Pemphigoid (tense blisters on the skin)
  2. Blood creatinine increased
  3. Fungal skin infection
  4. Genital infection fungal
  5. Ileus (a painful obstruction of the ileum or other part of the intestine)
  6. Milia (dead skin becomes trapped in small pockets at the surface of the skin or mouth)
  7. Mucosal erosion (peeling off of mucous membrane)
  8. Pruritus (severe itching of the skin)
  9. Septic shock (shock due to blood infection)
  10. Skin erosion (a discontinuity of the skin)

What are the common drug interactions of Onglyza and Silodosin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Blood creatinine increased
  2. Liver disorder (liver diseases)
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Dehydration (dryness resulting from the removal of water)
  5. Dysuria (painful or difficult urination)
  6. Erythema (redness of the skin)
  7. Fungal skin infection
  8. Genital infection fungal
  9. Milia (dead skin becomes trapped in small pockets at the surface of the skin or mouth)
  10. Mucosal erosion (peeling off of mucous membrane)

What are the existing conditions these people have? *

  1. Urination - Painful: 3 people, 25.00%
  2. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 3 people, 25.00%
  3. Lung Cancer - Non-Small Cell (lung cancer): 3 people, 25.00%
  4. High Blood Pressure: 3 people, 25.00%
  5. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 16.67%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 16.67%
  7. Gastric Disorder (disease of stomach): 2 people, 16.67%
  8. Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 16.67%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 16.67%
  10. Insomnia (sleeplessness): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Onglyza and Silodosin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Onglyza and Silodosin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Onglyza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Silodosin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Onglyza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Silodosin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on saxagliptin hydrochloride and silodosin (the active ingredients of Onglyza and Silodosin, respectively), and Onglyza and Silodosin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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