Onivyde and Lactulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Onivyde (irinotecan hydrochloride) and Lactulose (lactulose). Common drug interactions include decreased appetite among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Onivyde and Lactulose. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Onivyde?

Onivyde has active ingredients of irinotecan hydrochloride. eHealthMe is studying from 1,198 Onivyde users. Check the latest studies of Onivyde.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

On Jul, 06, 2026

12 people who take Onivyde and Lactulose together, and have interactions are studied.

Onivyde and Lactulose drug interactions.

What are the common drug interactions of Onivyde and Lactulose, by gender? *:

female:

Decreased appetite
Pneumonia
Confusional state
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pyrexia (fever)

male:

Nausea (feeling of having an urge to vomit)
Decreased appetite
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Failure to thrive (inadequate weight gain and physical growth in children)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypophagia (reduced food intake)
Infection
Leukocytosis (increased white blood cells)
Pulmonary embolism (blockage of the main artery of the lung)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Onivyde and Lactulose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Decreased appetite
Pneumonia
Dyspnoea (difficult or laboured respiration)
Pyrexia (fever)

50-59:

Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Failure to thrive (inadequate weight gain and physical growth in children)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypophagia (reduced food intake)
Infection
Leukocytosis (increased white blood cells)
Pulmonary embolism (blockage of the main artery of the lung)

60+:

Confusional state
Dehydration (dryness resulting from the removal of water)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the existing conditions these people have? *

Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 6 people, 50.00%
Back Pain: 6 people, 50.00%
Abdominal Pain: 6 people, 50.00%
Pancreatic Carcinoma (pancreatic cancer): 3 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%
Pain: 2 people, 16.67%
Oesophageal Carcinoma (cancer tumour of oesophagus): 1 person, 8.33%
Gastroesophageal Cancer: 1 person, 8.33%
Gastric Cancer (stomach cancer): 1 person, 8.33%
Colon Cancer: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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