Opdivo and Asa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Opdivo (nivolumab) and Asa (aspirin). Common drug interactions include arthralgia among females and malignant neoplasm progression among males.

The phase IV clinical study analyzes what interactions people have when they take Opdivo and Asa. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.

What is Asa?

Asa has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 32,557 Asa users. Check the latest studies of Asa.

On Jul, 26, 2026

32 people who take Opdivo and Asa together, and have interactions are studied.

What are the common drug interactions of Opdivo and Asa, by gender? *:

female:

Arthralgia (joint pain)
Contusion (a type of hematoma of tissue in which capillaries)
Migraine (headache)
Nasal discomfort
Pain in extremity
Rhinorrhoea (watery mucus discharge from the nose)
Swelling
Pain
Abdominal pain lower
Adverse event

male:

Malignant neoplasm progression (cancer tumour came back)
Dizziness
Pruritus (severe itching of the skin)
Radiation sickness syndrome (radiation toxicity)
Scratch
Skin discolouration (change of skin colour)
Hepatic enzyme increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Chest discomfort
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Opdivo and Asa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arthralgia (joint pain)
Contusion (a type of hematoma of tissue in which capillaries)
Migraine (headache)
Nasal discomfort
Pain in extremity
Rhinorrhoea (watery mucus discharge from the nose)
Swelling
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Vomiting

60+:

Malignant neoplasm progression (cancer tumour came back)
Dizziness
Skin discolouration (change of skin colour)
Hepatic enzyme increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Abdominal pain lower
Arthralgia (joint pain)
Autoimmune hepatitis
Balance disorder
Chest discomfort

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 7 people, 21.88%
Lung Neoplasm Malignant (cancer tumour of lung): 5 people, 15.62%
Malignant Melanoma (skin cancer rises from melancytes): 4 people, 12.50%
Neoplasm Malignant (cancer tumour): 3 people, 9.38%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 3 people, 9.38%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 3 people, 9.38%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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