Opdivo and Halcion drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Opdivo (nivolumab) and Halcion (triazolam). Common drug interactions include erythema among females and rhabdomyolysis among males.
The phase IV clinical study analyzes what interactions people have when they take Opdivo and Halcion. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Opdivo?
Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.
What is Halcion?
Halcion has active ingredients of triazolam. It is often used in insomnia. eHealthMe is studying from 8,268 Halcion users. Check the latest studies of Halcion.
19 people who take Opdivo and Halcion together, and have interactions are studied.

What are the common drug interactions of Opdivo and Halcion, by gender? *:
female:
- Erythema (redness of the skin)
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Asthenia (weakness)
- Hepatotoxicity (chemical-driven liver damage)
- Hypophysitis (inflammation of the pituitary gland)
- Upper limb fracture
- Cardiac amyloidosis (protein deposition in heart)
- Anaemia (lack of blood)
- Facial paralysis (loss of function of face muscle)
male:
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Erysipelas (bacterial skin infection)
- Performance status decreased
- Pulmonary toxicity (side effects on the lungs)
- Hypophysitis (inflammation of the pituitary gland)
- Cholangitis sclerosing (infection and obstruction of bile duct)
- Blood thyroid stimulating hormone decreased
- Secondary adrenocortical insufficiency (inadequate secretion of acth by the pituitary gland)
- Thyroiditis (inflammation of thyroid gland)
- Type 1 diabetes mellitus
What are the common drug interactions of Opdivo and Halcion, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Hypophysitis (inflammation of the pituitary gland)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Interstitial lung disease
- Secondary adrenocortical insufficiency (inadequate secretion of acth by the pituitary gland)
- Thyroiditis (inflammation of thyroid gland)
- Type 1 diabetes mellitus
- Upper limb fracture
- Cardiac amyloidosis (protein deposition in heart)
- Anaemia (lack of blood)
- Facial paralysis (loss of function of face muscle)
What are the existing conditions these people have? *
- Malignant Melanoma (skin cancer rises from melancytes): 9 people, 47.37%
- Oral Cancer (mouth cancer): 4 people, 21.05%
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 2 people, 10.53%
- Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 10.53%
- High Blood Pressure: 2 people, 10.53%
- Renal Cancer Stage Iv (the tumour has spread to areas beyond gerota's fascia and extends into the adrenal gland on the same side of the body as the tumour, possibly to lymph nodes, but not to other parts of the body): 1 person, 5.26%
- Non-Small Cell Lung Cancer Recurrent (type of epithelial lung cancer reoccurrence): 1 person, 5.26%
- Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 5.26%
- Lung Cancer - Non-Small Cell (lung cancer): 1 person, 5.26%
- Diabetes: 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Opdivo and Halcion?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Opdivo and Halcion:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Opdivo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Halcion:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Opdivo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Halcion and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nivolumab and triazolam (the active ingredients of Opdivo and Halcion, respectively), and Opdivo and Halcion (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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