Opsumit and Pred forte drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Opsumit (macitentan) and Pred forte (prednisolone acetate). Common drug interactions include hypotension among females.
The phase IV clinical study analyzes what interactions people have when they take Opsumit and Pred forte. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Opsumit?
Opsumit has active ingredients of macitentan. eHealthMe is studying from 67,926 Opsumit users. Check the latest studies of Opsumit.
What is Pred forte?
Pred forte has active ingredients of prednisolone acetate. It is often used in uveitis. eHealthMe is studying from 3,229 Pred forte users. Check the latest studies of Pred forte.
15 people who take Opsumit and Pred forte together, and have interactions are studied.

What are the common drug interactions of Opsumit and Pred Forte, by gender? *:
female:
- Hypotension (abnormally low blood pressure)
- Asthenia (weakness)
- Blood phosphorus decreased
- Blood potassium decreased
- Colitis (inflammation of colon)
- Culture stool positive
- Decreased appetite
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Dyspepsia (indigestion)
male:
n/a
What are the common drug interactions of Opsumit and Pred Forte, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal pain
- Abdominal pain upper
- Alanine aminotransferase increased
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Aphonia (inability to produce voice)
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Blood phosphorus decreased
- Blood potassium decreased
- Colitis (inflammation of colon)
40-49:
n/a
50-59:
n/a
60+:
- Dyspnoea (difficult or laboured respiration)
- Facial paralysis (loss of function of face muscle)
- Cardiac failure congestive
- Chronic kidney disease
- Confusional state
- Cough
- Cubital tunnel syndrome (a condition brought on by increased pressure on the ulnar nerve at the elbow)
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Dizziness
- Drug intolerance (drug sensitivity)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 11 people, 73.33%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 26.67%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.67%
- Cough: 1 person, 6.67%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.67%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Opsumit and Pred forte?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Opsumit (67,926 reports)
- Pred forte (3,229 reports)
Browse all drug interactions of Opsumit and Pred forte:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Opsumit:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pred forte:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Opsumit and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pred forte and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on macitentan and prednisolone acetate (the active ingredients of Opsumit and Pred forte, respectively), and Opsumit and Pred forte (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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