Opsumit and Temovate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Opsumit (macitentan) and Temovate (clobetasol propionate). Common drug interactions include burning sensation among females and bladder cancer among males.

The phase IV clinical study analyzes what interactions people have when they take Opsumit and Temovate. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Opsumit?

Opsumit has active ingredients of macitentan. eHealthMe is studying from 67,926 Opsumit users. Check the latest studies of Opsumit.

What is Temovate?

Temovate has active ingredients of clobetasol propionate. eHealthMe is studying from 1,392 Temovate users. Check the latest studies of Temovate.

On Jul, 11, 2026

21 people who take Opsumit and Temovate together, and have interactions are studied.

What are the common drug interactions of Opsumit and Temovate, by gender? *:

female:

Burning sensation
Cough
Dyspepsia (indigestion)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Oral discomfort (pain or irritation in mouth)
Abdominal pain lower
Diarrhoea haemorrhagic (bloody diarrhoea)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Mucous stools (mucous with stool)
Dyspnoea exertional (breathlessness or shortness of breath)

male:

Bladder cancer
Cardiac failure
Lung disorder (lung disease)
T-cell lymphoma (a blood cell cancer)

What are the common drug interactions of Opsumit and Temovate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Headache (pain in head)
Dyspnoea (difficult or laboured respiration)
Oral discomfort (pain or irritation in mouth)
Abdominal pain lower
Diarrhoea haemorrhagic (bloody diarrhoea)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Mucous stools (mucous with stool)
Dyspnoea exertional (breathlessness or shortness of breath)
Dysuria (painful or difficult urination)
Hypoxia (low oxygen in tissues)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 14 people, 66.67%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 12 people, 57.14%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 4 people, 19.05%
Interstitial Lung Disease: 4 people, 19.05%
Diarrhea: 4 people, 19.05%
Urinary Tract Infection: 3 people, 14.29%
Thyroid Diseases: 3 people, 14.29%
Swelling: 3 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
Cardiac Disorder: 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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