Opsumit and Valcyte drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Opsumit (macitentan) and Valcyte (valganciclovir hydrochloride). Common drug interactions include blood creatinine increased among females and agranulocytosis among males.

The phase IV clinical study analyzes what interactions people have when they take Opsumit and Valcyte. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Opsumit?

Opsumit has active ingredients of macitentan. eHealthMe is studying from 67,926 Opsumit users. Check the latest studies of Opsumit.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.

On Aug, 10, 2026

14 people who take Opsumit and Valcyte together, and have interactions are studied.

What are the common drug interactions of Opsumit and Valcyte, by gender? *:

female:

Blood creatinine increased
Cellulitis (infection under the skin)
Foot fracture
Neuropathic arthropathy (a progressive destruction of bone and joints)
Osteomyelitis (infection of bone)
Peripheral swelling
Purpura (purplish discoloration of the skin)
Renal transplant
Vasculitis (inflammation of a blood vessel or blood vessels)
Cervix enlargement

male:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Pain
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Liver transplant
Lung transplant
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal distension
Adverse drug reaction
Arthralgia (joint pain)

What are the common drug interactions of Opsumit and Valcyte, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Liver transplant
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)

60+:

Pain
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Renal transplant
Respiratory depression (respiration has a rate below 12 breaths)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Cellulitis (infection under the skin)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Foot fracture
Lung transplant

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 42.86%
Cytomegalovirus Infection: 4 people, 28.57%
Respiratory Depression (respiration has a rate below 12 breaths): 3 people, 21.43%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 7.14%
Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 1 person, 7.14%
Cor Pulmonale (enlargement of the right ventricle of the heart): 1 person, 7.14%
Chronic Kidney Disease: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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