Optivar and Lipitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Optivar (azelastine hydrochloride) and Lipitor (atorvastatin calcium). Common drug interactions include somnolence among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Optivar and Lipitor. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Optivar?

Optivar has active ingredients of azelastine hydrochloride. eHealthMe is studying from 367 Optivar users. Check the latest studies of Optivar.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,050 Lipitor users. Check the latest studies of Lipitor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

35 people who take Optivar and Lipitor together, and have interactions are studied.

What are the common drug interactions of Optivar and Lipitor, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Stress
Swelling
Therapeutic response decreased (less preventive response)
Tooth disorder (tooth disease)
Tremor (trembling or shaking movements in one or more parts of your body)
Tunnel vision (the loss of peripheral vision with retention of central vision)
Sinusitis (inflammation of sinus)
Candidiasis (candidiasis or thrush is a fungal infection)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

male:

Acute respiratory failure
Anaemia (lack of blood)
Proteinuria (presence of protein in the urine)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Weight decreased
Eating disorder
Weight increased
Death

What are the common drug interactions of Optivar and Lipitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Sinusitis (inflammation of sinus)
Candidiasis (candidiasis or thrush is a fungal infection)
Upper respiratory tract infection
Abdominal pain
Back pain
Constipation
Gastric ulcer (stomach ulcer)
Oedema peripheral (superficial swelling)
Oral candidiasis (fungal infection of mouth)
Pain in extremity

50-59:

Febrile neutropenia (fever with reduced white blood cells)
Haemoglobin decreased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Thrombocytopenia (decrease of platelets in blood)
Urinary tract infection
Chronic kidney disease
Deafness
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

60+:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Acute respiratory failure
Proteinuria (presence of protein in the urine)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Weight decreased
Eating disorder
Weight increased
Death

What are the existing conditions these people have? *

Pain: 7 people, 20.00%
Hypersensitivity: 7 people, 20.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 17.14%
Diabetes: 6 people, 17.14%
Dry Eyes (lack of adequate tears): 5 people, 14.29%
Oedema (fluid collection in tissue): 5 people, 14.29%
Depression: 5 people, 14.29%
Metastases To Central Nervous System (cancer spreads to central nervous system): 5 people, 14.29%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 11.43%
Immunodeficiency: 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

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