Oracea and Bupropion hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oracea (doxycycline) and Bupropion hydrochloride (bupropion hydrochloride). Common drug interactions include omphalitis among females.

The phase IV clinical study analyzes what interactions people have when they take Oracea and Bupropion hydrochloride. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Oracea?

Oracea has active ingredients of doxycycline. It is often used in rosacea. eHealthMe is studying from 1,272 Oracea users. Check the latest studies of Oracea.

What is Bupropion hydrochloride?

Bupropion hydrochloride has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 21,496 Bupropion hydrochloride users. Check the latest studies of Bupropion hydrochloride.

On Jul, 31, 2026

13 people who take Oracea and Bupropion hydrochloride together, and have interactions are studied.

Oracea and Bupropion hydrochloride drug interactions.

What are the common drug interactions of Oracea and Bupropion Hydrochloride, by gender? *:

female:

Omphalitis (medical term for infection of the umbilical cord)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Sinus disorder (disease of sinus)
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicidal ideation
Viral infection
Nasopharyngitis (inflammation of the nasopharynx)
Sinusitis (inflammation of sinus)
Chronic kidney disease

male:

n/a

What are the common drug interactions of Oracea and Bupropion Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)
Drug ineffective
Fatigue (feeling of tiredness)
Memory impairment

40-49:

n/a

50-59:

Diarrhoea
Nasopharyngitis (inflammation of the nasopharynx)
Omphalitis (medical term for infection of the umbilical cord)
Sinusitis (inflammation of sinus)
Sinus disorder (disease of sinus)
Viral infection

60+:

Chronic kidney disease

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 53.85%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 5 people, 38.46%
Mitral Valve Stenosis (narrowing of mitral valve): 5 people, 38.46%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 5 people, 38.46%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 30.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 2 people, 15.38%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 15.38%
Bacterial Infection: 2 people, 15.38%
Gouty Arthritis (joint inflammation with crystal formation): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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