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Oracea and Soma drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oracea (doxycycline) and Soma (carisoprodol). Common drug interactions include migraine among females.

The phase IV clinical study analyzes what interactions people have when they take Oracea and Soma. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Oracea?

Oracea has active ingredients of doxycycline. It is often used in rosacea. eHealthMe is studying from 1,272 Oracea users. Check the latest studies of Oracea.

What is Soma?

Soma has active ingredients of carisoprodol. It is often used in muscle spasms. eHealthMe is studying from 17,137 Soma users. Check the latest studies of Soma.

On Jul, 05, 2026

15 people who take Oracea and Soma together, and have interactions are studied.

Oracea and Soma drug interactions.

What are the common drug interactions of Oracea and Soma, by gender? *:

female:

  1. Migraine (headache)
  2. Depression
  3. Anxiety
  4. Blood sodium decreased
  5. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  6. Loss of consciousness
  7. Panic attack
  8. Stress
  9. Hypersensitivity
  10. Respiratory depression (respiration has a rate below 12 breaths)

male:

n/a

What are the common drug interactions of Oracea and Soma, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Drug ineffective
  2. Stress
  3. Suicidal ideation

40-49:

n/a

50-59:

n/a

60+:

  1. Road traffic accident
  2. Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

What are the existing conditions these people have? *

  1. Drowsiness: 14 people, 93.33%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 6.67%
  3. Stress And Anxiety: 1 person, 6.67%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
  5. Muscle Aches (muscle pain): 1 person, 6.67%
  6. Irritable Bowel Syndrome: 1 person, 6.67%
  7. Insomnia (sleeplessness): 1 person, 6.67%
  8. Hyperthyroidism (over activity of the thyroid gland): 1 person, 6.67%
  9. Depression: 1 person, 6.67%
  10. Affective Disorder (mental disorder): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Oracea and Soma?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oracea and Soma:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oracea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Soma:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oracea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Soma and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline and carisoprodol (the active ingredients of Oracea and Soma, respectively), and Oracea and Soma (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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