Oramorph sr and Codeine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oramorph sr (morphine sulfate) and Codeine sulfate (codeine sulfate). Common drug interactions include platelet count decreased among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Oramorph sr and Codeine sulfate. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Oramorph sr?

Oramorph sr has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 2,897 Oramorph sr users. Check the latest studies of Oramorph sr.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.

On Jul, 13, 2026

19 people who take Oramorph sr and Codeine sulfate together, and have interactions are studied.

Oramorph sr and Codeine sulfate drug interactions.

What are the common drug interactions of Oramorph Sr and Codeine Sulfate, by gender? *:

female:

Platelet count decreased
Alanine aminotransferase increased
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Dehydration (dryness resulting from the removal of water)
Drug toxicity
Duodenal obstruction (partial or complete obstruction of the duodenum)
Haemorrhage subcutaneous (bleeding from skin)
Multi-organ failure (multisystem organ failure)
Multiple drug overdose
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)

male:

Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
Death
Depression
Device related infection
Diarrhoea
Disease progression
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Fall
Fatigue (feeling of tiredness)

What are the common drug interactions of Oramorph Sr and Codeine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Chills (felling of cold)
Depressed level of consciousness
Dizziness
Dry mouth
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)

30-39:

n/a

40-49:

Platelet count decreased
Alanine aminotransferase increased
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Drug toxicity
Haemorrhage subcutaneous (bleeding from skin)
Multi-organ failure (multisystem organ failure)
Multiple drug overdose
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Respiratory failure (inadequate gas exchange by the respiratory system)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)

50-59:

Constipation
Cytomegalovirus infection
Death
Depression
Device related infection
Diarrhoea
Disease progression
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Fall
Fatigue (feeling of tiredness)

60+:

Hyperbilirubinaemia (excess of bilirubin in the blood)
Neutropenia (an abnormally low number of neutrophils)
Renal failure acute (rapid kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Glomerular filtration rate decreased
Duodenal obstruction (partial or complete obstruction of the duodenum)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 26.32%
Nausea (feeling of having an urge to vomit): 4 people, 21.05%
Diarrhea: 4 people, 21.05%
Abdominal Pain: 3 people, 15.79%
Headache (pain in head): 3 people, 15.79%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 15.79%
Enterococcal Infection: 3 people, 15.79%
Constipation: 2 people, 10.53%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 10.53%
Dyspnea (difficult or laboured breathing): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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