Orapred and Xopenex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Orapred (prednisolone sodium phosphate) and Xopenex (levalbuterol hydrochloride). Common drug interactions include conductive deafness among females and eczema among males.

The phase IV clinical study analyzes what interactions people have when they take Orapred and Xopenex. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Orapred?

Orapred has active ingredients of prednisolone sodium phosphate. It is often used in croup. eHealthMe is studying from 428 Orapred users. Check the latest studies of Orapred.

What is Xopenex?

Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.

On Jul, 08, 2026

26 people who take Orapred and Xopenex together, and have interactions are studied.

What are the common drug interactions of Orapred and Xopenex, by gender? *:

female:

Conductive deafness (deafness due to a problem in conducting sound waves)
Deafness neurosensory
Blood oestrogen increased
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Agitation (state of anxiety or nervous excitement)
Cough
Hot flush (sudden feelings of heat)
Insomnia (sleeplessness)
Pneumonia
Psychomotor hyperactivity (feelings of extreme restlessness)

male:

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Respiratory distress (difficulty in breathing)
Purpura (purplish discoloration of the skin)
Swelling face
Thrombocytopenia (decrease of platelets in blood)
Urticaria (rash of round, red welts on the skin that itch intensely)
Acute respiratory failure
Agitation (state of anxiety or nervous excitement)
Angioedema (rapid swelling of the dermis)
Bronchomalacia (bronchomalacia is caused by a deficiency in the cartilaginous rings)

What are the common drug interactions of Orapred and Xopenex, by age (0-1 to 60+)? *:

0-1:

Platelet count decreased
Purpura (purplish discoloration of the skin)
Respiratory distress (difficulty in breathing)
Thrombocytopenia (decrease of platelets in blood)
Acute respiratory failure
Angioedema (rapid swelling of the dermis)
Bronchomalacia (bronchomalacia is caused by a deficiency in the cartilaginous rings)
Bronchopulmonary dysplasia (chronic lung disorder in infants - enlargement of an organ or tissue by the proliferation of cells of an abnormal type)
Chronic respiratory failure
Drug ineffective

2-9:

Agitation (state of anxiety or nervous excitement)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Endocrine disorder (endocrine diseases are disorders of the endocrine system)
Flushing (the warm, red condition of human skin)
Growth retardation (delayed growth)
Hypertension (high blood pressure)
Increased activity

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Hot flush (sudden feelings of heat)

What are the existing conditions these people have? *

Cough: 4 people, 15.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
Allergic Rhinitis: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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