Orencia and Lys drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Orencia (abatacept) and Lys (lysine). Common drug interactions include c-reactive protein increased among females and foot deformity among males.

The phase IV clinical study analyzes what interactions people have when they take Orencia and Lys. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Orencia?

Orencia has active ingredients of abatacept. It is often used in rheumatoid arthritis. eHealthMe is studying from 135,415 Orencia users. Check the latest studies of Orencia.

What is Lys?

Lys has active ingredients of lysine. eHealthMe is studying from 16,532 Lys users. Check the latest studies of Lys.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

37 people who take Orencia and Lys together, and have interactions are studied.

What are the common drug interactions of Orencia and Lys, by gender? *:

female:

C-reactive protein increased
Decreased appetite
Dizziness
Drug intolerance (drug sensitivity)
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
General physical health deterioration (weak health status)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hepatic enzyme increased
Hypercholesterolaemia (high levels of cholesterol in the blood)

male:

Foot deformity (functional disability of foot)
Leiomyosarcoma (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue)

What are the common drug interactions of Orencia and Lys, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Parotitis (inflammation of a parotid gland)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arthralgia (joint pain)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Pain
Upper respiratory tract infection

60+:

Drug ineffective
Blood potassium decreased
Leiomyosarcoma (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue)
Local swelling (swelling at the site of some application of substance or injury)
Muscle spasms (muscle contraction)
Pain
Pain in extremity
Pancreatitis acute (sudden inflammation of pancreas)
Squamous cell carcinoma (a cancer of a kind of epithelial cell)
Vomiting

What are the existing conditions these people have? *

Indigestion: 11 people, 29.73%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 29.73%
Immunodeficiency Common Variable: 7 people, 18.92%
Stiff Person Syndrome: 4 people, 10.81%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 8.11%
High Blood Pressure: 3 people, 8.11%
Nausea And Vomiting: 2 people, 5.41%
Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 2 people, 5.41%
Fatigue (feeling of tiredness): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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