Valacyclovir and Orenitram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valacyclovir (valacyclovir hydrochloride) and Orenitram (treprostinil). Common drug interactions include chest discomfort among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Valacyclovir and Orenitram. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

What is Orenitram?

Orenitram has active ingredients of treprostinil. eHealthMe is studying from 17,714 Orenitram users. Check the latest studies of Orenitram.

On May, 11, 2026

15 people who take Valacyclovir and Orenitram together, and have interactions are studied.

Valacyclovir and Orenitram drug interactions.

What are the common drug interactions of Valacyclovir and Orenitram, by gender? *:

female:

Chest discomfort
Pain in extremity
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Chest pain
Myalgia (muscle pain)
Pain
Abdominal pain

male:

Arthralgia (joint pain)
Genital swelling
Groin pain
Infusion site erythema (reddening of the skin at infusion site)
Infusion site pain
Infusion site swelling
Pain
Pubic pain (pelvic pain)

What are the common drug interactions of Valacyclovir and Orenitram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)

50-59:

Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Dizziness
Dyspepsia (indigestion)
Pain
Pain in extremity
Pain in jaw
Dyspnoea (difficult or laboured respiration)
Pulmonary oedema (fluid accumulation in the lungs)

60+:

Fatigue (feeling of tiredness)
Arthralgia (joint pain)
Dyspepsia (indigestion)
Dysphagia (a condition in which swallowing is difficult or painful)
Eructation (release of gas from the digestive tract)
Sinusitis (inflammation of sinus)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tremor (trembling or shaking movements in one or more parts of your body)
Chest discomfort
Chest pain

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 15 people, 100.00%
Neuropathy Peripheral (surface nerve damage): 1 person, 6.67%
Indigestion: 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
High Blood Cholesterol: 1 person, 6.67%
Diarrhea: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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