Orenitram and Zolpidem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Orenitram (treprostinil) and Zolpidem (zolpidem tartrate). Common drug interactions include pulmonary hypertension among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Orenitram and Zolpidem. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Orenitram?

Orenitram has active ingredients of treprostinil. eHealthMe is studying from 17,714 Orenitram users. Check the latest studies of Orenitram.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

On Aug, 01, 2026

57 people who take Orenitram and Zolpidem together, and have interactions are studied.

Orenitram and Zolpidem drug interactions.

What are the common drug interactions of Orenitram and Zolpidem, by gender? *:

female:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Chest discomfort
Hyperhidrosis (abnormally increased sweating)
Catheter site related reaction
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Erythema (redness of the skin)
Contusion (a type of hematoma of tissue in which capillaries)
Pain in extremity
Hospitalisation
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

male:

Diarrhoea
Flushing (the warm, red condition of human skin)
Chest discomfort
Chest pain
Heart rate increased
Abdominal discomfort
Blood pressure increased
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Photosensitivity reaction

What are the common drug interactions of Orenitram and Zolpidem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Pain in extremity
Chest pain
Disease progression
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Blood pressure decreased
Oxygen saturation decreased
Drug ineffective
Oxygen consumption increased

40-49:

Diarrhoea
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Vomiting
Dizziness
Dyspnoea exertional (breathlessness or shortness of breath)
Anaemia (lack of blood)
Cellulitis (infection under the skin)
Crying

50-59:

Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Nodule (a growth of abnormal tissue)
Non-cardiac chest pain
Occult blood positive
Oedema (fluid collection in tissue)
Palpitations (feelings or sensations that your heart is pounding or racing)
Photosensitivity reaction

60+:

Nausea (feeling of having an urge to vomit)
Pain
Blood glucose decreased
Bone disorder
Bronchial disorder
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Disease progression
Dizziness
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 47 people, 82.46%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 8.77%
Nausea (feeling of having an urge to vomit): 4 people, 7.02%

* Approximation only. Some reports may have incomplete information.

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