Ornithine and Valproic acid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ornithine (ornithine) and Valproic acid (valproic acid). Common drug interactions include stevens-johnson syndrome among females.
The phase IV clinical study analyzes what interactions people have when they take Ornithine and Valproic acid. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Ornithine?
Ornithine has active ingredients of ornithine. eHealthMe is studying from 591 Ornithine users. Check the latest studies of Ornithine.
What is Valproic acid?
Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.
16 people who take Ornithine and Valproic acid together, and have interactions are studied.

What are the common drug interactions of Ornithine and Valproic Acid, by gender? *:
female:
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
male:
n/a
What are the common drug interactions of Ornithine and Valproic Acid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Nuclear magnetic resonance imaging brain
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
- Body temperature increased
- Candidiasis (candidiasis or thrush is a fungal infection)
- Drug ineffective
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
- Loss of consciousness
10-19:
n/a
20-29:
n/a
30-39:
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
40-49:
n/a
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Vitamin B1 Deficiency: 12 people, 75.00%
- Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 12 people, 75.00%
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 12 people, 75.00%
- Cardiac Failure: 12 people, 75.00%
- Constipation: 12 people, 75.00%
- Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 12 people, 75.00%
- Flatulence (flatus expelled through the anus): 12 people, 75.00%
- Gallstones (stone formation by bile component): 12 people, 75.00%
- High Blood Pressure: 12 people, 75.00%
- Infection: 12 people, 75.00%
* Approximation only. Some reports may have incomplete information.
Do you take Ornithine and Valproic acid?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Ornithine (591 reports)
- Valproic acid (36,193 reports)
Browse all drug interactions of Ornithine and Valproic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ornithine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valproic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ornithine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Valproic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ornithine and valproic acid (the active ingredients of Ornithine and Valproic acid, respectively), and Ornithine and Valproic acid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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