Orudis and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Orudis (ketoprofen) and Atarax (hydroxyzine hydrochloride). Common drug interactions include arrhythmia among females and femur fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Orudis and Atarax. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Orudis?

Orudis has active ingredients of ketoprofen. eHealthMe is studying from 932 Orudis users. Check the latest studies of Orudis.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.



On Aug, 07, 2026

18 people who take Orudis and Atarax together, and have interactions are studied.

Orudis and Atarax drug interactions.

What are the common drug interactions of Orudis and Atarax, by gender? *:

female:

  1. Arrhythmia (irregular heartbeat)
  2. Cold-stimulus headache (headache by cold exposure)
  3. Femoral neck fracture (neck of femur bone fracture)
  4. Initial insomnia (feeling of inadequate or poor-quality sleep)
  5. Tension headache
  6. Aggression
  7. Apathy
  8. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  9. Disturbance in attention
  10. Dizziness

male:

  1. Femur fracture
  2. Pyrexia (fever)
  3. Device related infection
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Fatigue (feeling of tiredness)
  7. Hypersomnia (excessive daytime sleepiness (eds))
  8. Hypotonia (low muscle tone)
  9. Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Orudis and Atarax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Cold-stimulus headache (headache by cold exposure)
  2. Device related infection
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Initial insomnia (feeling of inadequate or poor-quality sleep)
  5. Tension headache
  6. Aggression
  7. Apathy
  8. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  9. Disturbance in attention
  10. Dizziness

50-59:

  1. Femoral neck fracture (neck of femur bone fracture)

60+:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  2. Fatigue (feeling of tiredness)
  3. Hypersomnia (excessive daytime sleepiness (eds))
  4. Hypotonia (low muscle tone)
  5. Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

  1. Burkitt Lymphoma (cancer of the lymphatic system): 8 people, 44.44%
  2. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 38.89%
  3. Fever: 4 people, 22.22%
  4. Femur Fracture: 4 people, 22.22%
  5. Osteoporosis (bones weak and more likely to break): 2 people, 11.11%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
  7. Quit Smoking: 1 person, 5.56%
  8. Pain: 1 person, 5.56%
  9. High Blood Cholesterol: 1 person, 5.56%
  10. Depression: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Orudis and Atarax?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Orudis and Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Orudis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Orudis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atarax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ketoprofen and hydroxyzine hydrochloride (the active ingredients of Orudis and Atarax, respectively), and Orudis and Atarax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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