Otezla and Bydureon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Otezla (apremilast) and Bydureon (exenatide synthetic). Common drug interactions include nausea among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Otezla and Bydureon. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Otezla?

Otezla has active ingredients of apremilast. It is often used in psoriatic arthritis. eHealthMe is studying from 146,254 Otezla users. Check the latest studies of Otezla.

What is Bydureon?

Bydureon has active ingredients of exenatide synthetic. It is often used in type 2 diabetes. eHealthMe is studying from 24,309 Bydureon users. Check the latest studies of Bydureon.

On Jul, 17, 2026

31 people who take Otezla and Bydureon together, and have interactions are studied.

What are the common drug interactions of Otezla and Bydureon, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Rash
Diarrhoea
Fungal infection
Psoriasis (immune-mediated disease that affects the skin)
Decreased appetite
Vomiting
Weight decreased
Abdominal pain upper
Constipation

male:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Presyncope
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Vomiting
Discomfort
Drug ineffective
Pain
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)

What are the common drug interactions of Otezla and Bydureon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective

40-49:

Asthma

50-59:

Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Constipation
Rash
Urinary tract infection
Blood glucose increased
Muscle spasms (muscle contraction)
Drug ineffective
Psoriasis (immune-mediated disease that affects the skin)
Dyspnoea (difficult or laboured respiration)

60+:

Psoriasis (immune-mediated disease that affects the skin)
Rash
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Nausea (feeling of having an urge to vomit)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Presyncope
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Vomiting
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Headache (pain in head)

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 19 people, 61.29%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 13 people, 41.94%
Diabetes: 6 people, 19.35%
High Blood Pressure: 5 people, 16.13%
High Blood Cholesterol: 5 people, 16.13%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 12.90%
Depression: 4 people, 12.90%

* Approximation only. Some reports may have incomplete information.

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