Otezla and Ssd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Otezla (apremilast) and Ssd (silver sulfadiazine). Common drug interactions include psoriasis among females and adverse reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Otezla and Ssd. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Otezla?

Otezla has active ingredients of apremilast. It is often used in psoriatic arthritis. eHealthMe is studying from 146,254 Otezla users. Check the latest studies of Otezla.

What is Ssd?

Ssd has active ingredients of silver sulfadiazine. eHealthMe is studying from 249 Ssd users. Check the latest studies of Ssd.

On Jul, 10, 2026

22 people who take Otezla and Ssd together, and have interactions are studied.

What are the common drug interactions of Otezla and Ssd, by gender? *:

female:

Psoriasis (immune-mediated disease that affects the skin)
Stress
Drug hypersensitivity
Hepatic enzyme increased
Rash
Allergy to chemicals
Breast cancer
Diarrhoea
Fatigue (feeling of tiredness)
Headache (pain in head)

male:

Adverse reaction
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug effect decreased
Nephrolithiasis (calculi in the kidneys)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Pulmonary valve incompetence
Sexual abuse
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Spinal cord injury

What are the common drug interactions of Otezla and Ssd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Psoriasis (immune-mediated disease that affects the skin)

30-39:

Adverse reaction

40-49:

Allergy to chemicals
Psoriasis (immune-mediated disease that affects the skin)
Stress

50-59:

Nausea (feeling of having an urge to vomit)
Pain
Psoriasis (immune-mediated disease that affects the skin)
Rash
Diarrhoea
Fatigue (feeling of tiredness)
Headache (pain in head)

60+:

Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Stress
Breast cancer
Hospitalisation
Wound

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 13 people, 59.09%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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