Ovral and Prevacid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ovral (ethinyl estradiol; norgestrel) and Prevacid (lansoprazole). Common drug interactions include arthropathy among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ovral and Prevacid. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Ovral?

Ovral has active ingredients of ethinyl estradiol; norgestrel. It is often used in birth control. eHealthMe is studying from 1,571 Ovral users. Check the latest studies of Ovral.

What is Prevacid?

Prevacid has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 130,714 Prevacid users. Check the latest studies of Prevacid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

47 people who take Ovral and Prevacid together, and have interactions are studied.

What are the common drug interactions of Ovral and Prevacid, by gender? *:

female:

Arthropathy
Blood immunoglobulin e increased
Cardiac arrest
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Feeling hot and cold
Hepatic neoplasm (liver tumour)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
Muscle cramp (painful sensation caused by muscle contraction)

male:

Abdominal pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Electrocardiogram abnormal
Fatigue (feeling of tiredness)
Heart rate irregular
Hypertensive heart disease
Myocardial infarction old (old destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Oedema (fluid collection in tissue)
Orthopnoea (shortness of breath (dyspnea) when lying down)

What are the common drug interactions of Ovral and Prevacid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Feeling hot and cold
Muscle cramp (painful sensation caused by muscle contraction)
Pain in extremity
Psychosomatic disease (situation in which the mind influences the body to create or complicate an illness)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Syncope (loss of consciousness with an inability to maintain postural tone)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

20-29:

Nausea (feeling of having an urge to vomit)
Abdominal pain
Abdominal tenderness
Hepatic neoplasm (liver tumour)
Abdominal pain upper
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

30-39:

Dysfunctional uterine bleeding
Ear pain
Fibula fracture
Gait disturbance
Joint range of motion decreased (disease of joint movement)
Osteopenia (a condition where bone mineral density is lower than normal)
Rash pruritic (redness with itching)
Urinary tract infection
Back pain
Eczema infected (eczema due to bacterial infection or with bacterial infection)

40-49:

Anxiety
Arthropathy
Cardiac arrest
Depression
Dyspnoea (difficult or laboured respiration)
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
Ovarian cyst (fluid filled sac of the ovary)
Pneumonia
Post-traumatic stress disorder
Ventricular fibrillation (abnormally irregular heart rhythm)

50-59:

Abdominal pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Electrocardiogram abnormal
Fatigue (feeling of tiredness)
Heart rate irregular
Hypertensive heart disease
Myocardial infarction old (old destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

n/a

What are the existing conditions these people have? *

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 19 people, 40.43%
Stress And Anxiety: 5 people, 10.64%
Pain: 4 people, 8.51%
High Blood Pressure: 4 people, 8.51%
Urinary Tract Infection: 3 people, 6.38%
Sleep Disorder: 3 people, 6.38%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 6.38%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.38%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 6.38%
Gout (uric acid crystals building up in the body): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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