Oxazepam and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxazepam (oxazepam) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include cyanosis among females and multiple drug overdose among males.

The phase IV clinical study analyzes what interactions people have when they take Oxazepam and Hydrocodone. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Oxazepam?

Oxazepam has active ingredients of oxazepam. It is often used in stress and anxiety. eHealthMe is studying from 23,836 Oxazepam users. Check the latest studies of Oxazepam.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

21 people who take Oxazepam and Hydrocodone together, and have interactions are studied.

Oxazepam and Hydrocodone drug interactions.

What are the common drug interactions of Oxazepam and Hydrocodone, by gender? *:

female:

Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug abuse
Pain
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Skin lesion
Weight decreased
Depression
Chronic kidney disease
Alopecia (absence of hair from areas of the body)

male:

Multiple drug overdose
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Drug screen positive
Endocardial fibrosis (cardiac fibrosis refers to an abnormal thickening of the heart valves)
Haemorrhage (bleeding)
Multiple drug overdose accidental
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Ventricular fibrillation (abnormally irregular heart rhythm)
Pulmonary congestion (congestion in the lungs)

What are the common drug interactions of Oxazepam and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Multiple drug overdose

20-29:

Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug abuse

30-39:

n/a

40-49:

Chronic kidney disease
Drug screen positive
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Blood creatine increased
Bone density decreased
Depression
Emotional distress
Pain
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)

50-59:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Multiple drug overdose

60+:

Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Asthenia (weakness)
Back pain
Breast disorder
Breast mass
Cardiac disorder
Crying
Depression
Dizziness

What are the existing conditions these people have? *

Pain: 2 people, 9.52%
Insomnia (sleeplessness): 2 people, 9.52%
Asthma: 2 people, 9.52%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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