Oxbryta and Colchicine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxbryta (voxelotor) and Colchicine (colchicine). Common drug interactions include nausea among females and depressed mood among males.

The phase IV clinical study analyzes what interactions people have when they take Oxbryta and Colchicine. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Oxbryta?

Oxbryta has active ingredients of voxelotor. eHealthMe is studying from 24,969 Oxbryta users. Check the latest studies of Oxbryta.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.

On Jul, 31, 2026

27 people who take Oxbryta and Colchicine together, and have interactions are studied.

Oxbryta and Colchicine drug interactions.

What are the common drug interactions of Oxbryta and Colchicine, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Balance disorder
Decreased appetite
Diarrhoea
Fall
Fatigue (feeling of tiredness)
Hypervolaemia (abnormally increased volume of blood)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Muscle atrophy (a decrease in the mass of the muscle)

male:

Depressed mood
Diarrhoea
Proteinuria (presence of protein in the urine)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Insomnia (sleeplessness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Rash papular (redness with papule)
Back pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Oxbryta and Colchicine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Osteomyelitis (infection of bone)
Renal impairment (severely reduced kidney function)
Ulcer
Wound infection pseudomonas

50-59:

Fatigue (feeling of tiredness)
Headache (pain in head)
Asthenia (weakness)
Diarrhoea
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Nausea (feeling of having an urge to vomit)
Photosensitivity reaction
Pruritus (severe itching of the skin)
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Balance disorder
Parkinson's disease
Speech disorder
Tremor (trembling or shaking movements in one or more parts of your body)
Weight decreased
Alopecia (absence of hair from areas of the body)
Decreased appetite
Fall
Hypervolaemia (abnormally increased volume of blood)

What are the existing conditions these people have? *

Pain: 5 people, 18.52%
Irritable Bowel Syndrome: 3 people, 11.11%
Stress And Anxiety: 2 people, 7.41%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 7.41%
Iron Overload: 2 people, 7.41%
Insomnia (sleeplessness): 2 people, 7.41%
Inflammation: 2 people, 7.41%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.41%
High Blood Pressure: 2 people, 7.41%
Acute Kidney Failure: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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