Oxervate and Zylet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxervate (cenegermin-bkbj) and Zylet (loteprednol etabonate; tobramycin). Common drug interactions include eye pain among females and eye pain among males.

The phase IV clinical study analyzes what interactions people have when they take Oxervate and Zylet. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Oxervate?

Oxervate has active ingredients of cenegermin-bkbj. eHealthMe is studying from 7,219 Oxervate users. Check the latest studies of Oxervate.

What is Zylet?

Zylet has active ingredients of loteprednol etabonate; tobramycin. eHealthMe is studying from 493 Zylet users. Check the latest studies of Zylet.

On Jul, 12, 2026

18 people who take Oxervate and Zylet together, and have interactions are studied.

What are the common drug interactions of Oxervate and Zylet, by gender? *:

female:

Eye pain
Eye irritation
Photophobia (extreme sensitivity to light)
Eye discharge
Eye swelling
Lacrimation increased
Headache (pain in head)
Rhinorrhoea (watery mucus discharge from the nose)
Toothache (tooth pain)
Feeling hot

male:

Eye pain
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Photophobia (extreme sensitivity to light)
Somnolence (a state of near-sleep, a strong desire for sleep)
Visual impairment
Lacrimation increased
Drug ineffective
Foreign body sensation in eyes (feeling of something in eye)
Eye swelling
Ocular hyperaemia (an abnormally large amount of blood in eye)

What are the common drug interactions of Oxervate and Zylet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Eye irritation

60+:

Eye pain
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Photophobia (extreme sensitivity to light)
Drug ineffective
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Eye swelling
Headache (pain in head)
Lacrimation increased
Somnolence (a state of near-sleep, a strong desire for sleep)
Visual impairment

What are the existing conditions these people have? *

Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 17 people, 94.44%
Ulcerative Keratitis (ulcerative inflammation of the cornea): 4 people, 22.22%
Hypoaesthesia Eye (reduced sense of touch or sensation on eyes): 1 person, 5.56%
Herpes Simplex (herpes simplex is a common viral infection): 1 person, 5.56%
Herpes Ophthalmic (eye infection caused by herpes simplex virus (hsv)): 1 person, 5.56%
Dry Eyes (lack of adequate tears): 1 person, 5.56%
Corneal Disorder: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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