Oxycodone and acetaminophen and Dyazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride) and Dyazide (hydrochlorothiazide; triamterene). Common drug interactions include non-alcoholic steatohepatitis among females and burning sensation among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and acetaminophen and Dyazide. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.



On Jul, 27, 2026

16 people who take Oxycodone and acetaminophen and Dyazide together, and have interactions are studied.

Oxycodone and acetaminophen and Dyazide drug interactions.

What are the common drug interactions of Oxycodone And Acetaminophen and Dyazide, by gender? *:

female:

  1. Non-alcoholic steatohepatitis (liver inflammation caused by a build up of fat in the liver)
  2. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  3. Tooth extraction
  4. Arthralgia (joint pain)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Hepatic enzyme increased
  8. Incoherent (talking in a confused and unclear way)
  9. Knee arthroplasty
  10. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

male:

  1. Burning sensation
  2. Gait disturbance
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Memory impairment
  5. Pain in extremity
  6. Therapeutic response unexpected
  7. Visual acuity reduced (reduced clearness of vision)
  8. Adverse event
  9. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  10. Hypovolaemic shock (shock caused by severe blood or fluid loss)

What are the common drug interactions of Oxycodone And Acetaminophen and Dyazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hypovolaemic shock (shock caused by severe blood or fluid loss)
  2. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)

50-59:

  1. Balance disorder
  2. Cardiac disorder
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Diabetes mellitus inadequate control
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Dysarthria (speech disorder)
  7. Dystonia (abnormal muscle tone)
  8. Encephalopathy (functioning of the brain is affected by some agent or condition)
  9. Endocarditis (inflammation in heart muscle)
  10. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)

60+:

  1. Arthralgia (joint pain)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Hepatic enzyme increased
  4. Incoherent (talking in a confused and unclear way)
  5. Knee arthroplasty
  6. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 56.25%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 50.00%
  3. Rickets (softening of bones): 3 people, 18.75%
  4. Rashes (redness): 3 people, 18.75%
  5. Oral Herpes (viral infection of mouth): 3 people, 18.75%
  6. Back Pain: 3 people, 18.75%
  7. Burning Feet Syndrome (burning sensation in the sole of the foot): 3 people, 18.75%
  8. Drowsiness: 3 people, 18.75%
  9. Gait Disturbance: 3 people, 18.75%
  10. Breakthrough Pain: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and acetaminophen and Dyazide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and acetaminophen and Dyazide:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone and acetaminophen:

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Browse all side effects of Dyazide:

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Browse all interactions between Oxycodone and acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dyazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride and hydrochlorothiazide; triamterene (the active ingredients of Oxycodone and acetaminophen and Dyazide, respectively), and Oxycodone and acetaminophen and Dyazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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