Oxycodone and acetaminophen and Pyridium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride) and Pyridium (phenazopyridine hydrochloride). Common drug interactions include migraine among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and acetaminophen and Pyridium. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Pyridium?

Pyridium has active ingredients of phenazopyridine hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 1,841 Pyridium users. Check the latest studies of Pyridium.



On Jul, 20, 2026

20 people who take Oxycodone and acetaminophen and Pyridium together, and have interactions are studied.

Oxycodone and acetaminophen and Pyridium drug interactions.

What are the common drug interactions of Oxycodone And Acetaminophen and Pyridium, by gender? *:

female:

  1. Migraine (headache)
  2. Pyrexia (fever)
  3. Asthenia (weakness)
  4. Bone loss
  5. Bone pain
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Chronic kidney disease
  8. Diarrhoea
  9. Fall
  10. Hypersomnia (excessive daytime sleepiness (eds))

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Oxycodone And Acetaminophen and Pyridium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Short-bowel syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing)
  2. Thrombosis (formation of a blood clot inside a blood vessel)
  3. Vomiting
  4. Chronic kidney disease
  5. Renal failure (kidney dysfunction)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Non-alcoholic steatohepatitis (liver inflammation caused by a build up of fat in the liver)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  10. Tooth extraction

60+:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Arthralgia (joint pain)
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Asthenia (weakness)
  5. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  6. Bacterial infection
  7. Bone loss
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Cataract (clouding of the lens inside the eye)
  10. Cystitis interstitial (unknown cause characterized by bladder pain)

What are the existing conditions these people have? *

  1. Depression: 9 people, 45.00%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 35.00%
  3. Stress And Anxiety: 7 people, 35.00%
  4. Asthma: 7 people, 35.00%
  5. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 7 people, 35.00%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 35.00%
  7. High Blood Cholesterol: 5 people, 25.00%
  8. Infection: 5 people, 25.00%
  9. Diabetes: 4 people, 20.00%
  10. High Blood Pressure: 4 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and acetaminophen and Pyridium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and acetaminophen and Pyridium:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pyridium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pyridium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride and phenazopyridine hydrochloride (the active ingredients of Oxycodone and acetaminophen and Pyridium, respectively), and Oxycodone and acetaminophen and Pyridium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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