Oxycodone and acetaminophen and Ranolazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride) and Ranolazine (ranolazine). Common drug interactions include death among females and liver disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and acetaminophen and Ranolazine. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Ranolazine?

Ranolazine has active ingredients of ranolazine. eHealthMe is studying from 9,939 Ranolazine users. Check the latest studies of Ranolazine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

18 people who take Oxycodone and acetaminophen and Ranolazine together, and have interactions are studied.

Oxycodone and acetaminophen and Ranolazine drug interactions.

What are the common drug interactions of Oxycodone And Acetaminophen and Ranolazine, by gender? *:

female:

Death
Fall
Headache (pain in head)
Arthralgia (joint pain)
Bladder disorder
Breast cellulitis (spreading, acute inflammation of beast skin)
Depression
Dyspnoea (difficult or laboured respiration)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Eye movement disorder

male:

Liver disorder (liver diseases)
Renal impairment (severely reduced kidney function)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Completed suicide (act of taking one's own life)
Death
Diarrhoea
Extrasystoles
Rash
Upper respiratory tract infection
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

What are the common drug interactions of Oxycodone And Acetaminophen and Ranolazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Headache (pain in head)

50-59:

Abdominal pain
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Rash

60+:

Liver disorder (liver diseases)
Renal impairment (severely reduced kidney function)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Fall
Neurodegenerative disorder (progressive loss of structure or function of neurons and death of neuron)
Parkinson's disease
Spinal fracture (fracture in one of vertebrae)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Death
Upper respiratory tract infection

What are the existing conditions these people have? *

Chest Pain: 5 people, 27.78%
High Blood Cholesterol: 4 people, 22.22%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 3 people, 16.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 16.67%
Prostatomegaly (enlargement of the prostate): 3 people, 16.67%
Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 3 people, 16.67%
Metastatic Neoplasm (spreadable cancer tumour): 3 people, 16.67%
Heart Attack: 3 people, 16.67%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 16.67%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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