Oxycodone and acetaminophen and Rapamune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride) and Rapamune (sirolimus). Common drug interactions include renal failure among females and escherichia infection among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and acetaminophen and Rapamune. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

11 people who take Oxycodone and acetaminophen and Rapamune together, and have interactions are studied.

Oxycodone and acetaminophen and Rapamune drug interactions.

What are the common drug interactions of Oxycodone And Acetaminophen and Rapamune, by gender? *:

female:

Renal failure (kidney dysfunction)
Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Chronic kidney disease
Fatigue (feeling of tiredness)
Headache (pain in head)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Mouth ulceration (mouth ulcers)
Neurological symptom (symptoms of nervous system disease)
Swelling face

male:

Escherichia infection (bacterial infection by escherichia coli)
Limb injury
Neuropathy peripheral (surface nerve damage)
Prostate cancer
Thrombosis (formation of a blood clot inside a blood vessel)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Sepsis (a severe blood infection that can lead to organ failure and death)
Blood creatinine increased
Chronic kidney disease
Graft loss (graft failure)

What are the common drug interactions of Oxycodone And Acetaminophen and Rapamune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood glucose increased
Blood magnesium decreased
Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Renal failure (kidney dysfunction)
Renal pain (kidney pain)

30-39:

Blood creatinine increased
Graft loss (graft failure)
Thrombosis (formation of a blood clot inside a blood vessel)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)

40-49:

Chronic kidney disease
Escherichia infection (bacterial infection by escherichia coli)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Limb injury
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

n/a

60+:

Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Nasopharyngitis (inflammation of the nasopharynx)
Neuropathy peripheral (surface nerve damage)
Prostate cancer
Fatigue (feeling of tiredness)
Headache (pain in head)
Mouth ulceration (mouth ulcers)
Neurological symptom (symptoms of nervous system disease)
Swelling face

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 36.36%
Anaemia (lack of blood): 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Hyperkalemia (damage to or disease of the kidney): 2 people, 18.18%
Gout (uric acid crystals building up in the body): 2 people, 18.18%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 18.18%
Hypoglycemia (low blood sugar): 2 people, 18.18%
Chest Pain: 2 people, 18.18%
Infection: 2 people, 18.18%
Inflammation: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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