Oxycodone and acetaminophen and Valerian drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride) and Valerian (valerian). Common drug interactions include enuresis among females and barrett's oesophagus among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and acetaminophen and Valerian. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Valerian?

Valerian has active ingredients of valerian. It is often used in insomnia. eHealthMe is studying from 1,271 Valerian users. Check the latest studies of Valerian.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

16 people who take Oxycodone and acetaminophen and Valerian together, and have interactions are studied.

Oxycodone and acetaminophen and Valerian drug interactions.

What are the common drug interactions of Oxycodone And Acetaminophen and Valerian, by gender? *:

female:

Enuresis (repeated inability to control urination)
Erythema (redness of the skin)
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Joint swelling
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain in extremity
Peripheral swelling
Post procedural complication

male:

Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Drug ineffective
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)

What are the common drug interactions of Oxycodone And Acetaminophen and Valerian, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Surgery
Wrist surgery

60+:

Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain in extremity
Peripheral swelling
Post procedural complication
Surgery
Weight decreased
Depression

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 75.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 50.00%
Sleep Disorder: 4 people, 25.00%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 25.00%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 25.00%
Dry Mouth: 4 people, 25.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 25.00%
Drowsiness: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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