Oxycodone and acetaminophen and Votrient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride) and Votrient (pazopanib hydrochloride). Common drug interactions include blood pressure increased among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and acetaminophen and Votrient. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 25,347 Votrient users. Check the latest studies of Votrient.



On Jul, 27, 2026

28 people who take Oxycodone and acetaminophen and Votrient together, and have interactions are studied.

Oxycodone and acetaminophen and Votrient drug interactions.

What are the common drug interactions of Oxycodone And Acetaminophen and Votrient, by gender? *:

female:

  1. Blood pressure increased
  2. Malignant neoplasm progression (cancer tumour came back)
  3. Decreased appetite
  4. Hair colour changes
  5. Migraine with aura (headache with vision weakness)
  6. Rash
  7. Renal cancer stage iv (the tumour has spread to areas beyond gerota's fascia and extends into the adrenal gland on the same side of the body as the tumour, possibly to lymph nodes, but not to other parts of the body)
  8. Stomatitis (inflammation of mucous membrane of mouth)
  9. Abdominal discomfort
  10. Diarrhoea

male:

  1. Fatigue (feeling of tiredness)
  2. Drug ineffective
  3. Metastases to liver (cancer spreads to liver)
  4. Metastases to lung (cancer spreads to lung)
  5. Metastatic pain (pain due to cancer spread)
  6. Wound complication
  7. Nausea (feeling of having an urge to vomit)
  8. Death
  9. Metastases to bone (cancer spreads to bone)
  10. Diarrhoea

What are the common drug interactions of Oxycodone And Acetaminophen and Votrient, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Death
  2. Diarrhoea
  3. Nausea (feeling of having an urge to vomit)

50-59:

  1. Blood pressure increased
  2. Decreased appetite
  3. Hair colour changes
  4. Migraine with aura (headache with vision weakness)
  5. Nausea (feeling of having an urge to vomit)
  6. Wound complication

60+:

  1. Blood pressure increased
  2. Diarrhoea
  3. Disease progression
  4. Localised infection (infection at the single location)
  5. Dyspepsia (indigestion)
  6. Fatigue (feeling of tiredness)
  7. Malignant neoplasm progression (cancer tumour came back)
  8. Nausea (feeling of having an urge to vomit)
  9. Rash
  10. Renal cancer stage iv (the tumour has spread to areas beyond gerota's fascia and extends into the adrenal gland on the same side of the body as the tumour, possibly to lymph nodes, but not to other parts of the body)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 20 people, 71.43%
  2. Stress And Anxiety: 3 people, 10.71%
  3. Constipation: 3 people, 10.71%
  4. Itching: 3 people, 10.71%
  5. High Blood Cholesterol: 2 people, 7.14%
  6. Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 2 people, 7.14%
  7. Cellulitis (infection under the skin): 2 people, 7.14%
  8. Depression: 2 people, 7.14%
  9. Fungal Skin Infection: 2 people, 7.14%
  10. Gastric Ulcer (stomach ulcer): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and acetaminophen and Votrient?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and acetaminophen and Votrient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone and acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Votrient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Votrient and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride and pazopanib hydrochloride (the active ingredients of Oxycodone and acetaminophen and Votrient, respectively), and Oxycodone and acetaminophen and Votrient (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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