Oxycodone and acetaminophen and Welchol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride) and Welchol (colesevelam hydrochloride). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and acetaminophen and Welchol. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

47 people who take Oxycodone and acetaminophen and Welchol together, and have interactions are studied.

Oxycodone and acetaminophen and Welchol drug interactions.

What are the common drug interactions of Oxycodone And Acetaminophen and Welchol, by gender? *:

female:

Chronic kidney disease
Fall
Renal disorder (kidney disease)
Weight decreased
Dehydration (dryness resulting from the removal of water)
Dizziness
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Sinusitis (inflammation of sinus)

male:

Chronic kidney disease
Drug ineffective
Road traffic accident
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Constipation
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Hot flush (sudden feelings of heat)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Osteomyelitis (infection of bone)

What are the common drug interactions of Oxycodone And Acetaminophen and Welchol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

30-39:

n/a

40-49:

Chronic kidney disease
Drug ineffective
Renal disorder (kidney disease)
Thyroidectomy
Weight decreased
Anxiety
Blindness
Bone density decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

50-59:

Stent occlusion (blockage of stent)
Chronic kidney disease
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Lung infection
Malaise (a feeling of general discomfort or uneasiness)
Productive cough
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 21 people, 44.68%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 19 people, 40.43%
High Blood Pressure: 9 people, 19.15%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 19.15%
Infection: 8 people, 17.02%
Diabetes: 8 people, 17.02%
Headache (pain in head): 6 people, 12.77%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 12.77%
Diarrhea: 6 people, 12.77%
Migraine (headache): 6 people, 12.77%

* Approximation only. Some reports may have incomplete information.

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