Oxycodone hydrochloride and Chantix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Chantix (varenicline tartrate). Common drug interactions include gait disturbance among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Chantix. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Chantix?

Chantix has active ingredients of varenicline tartrate. It is often used in quit smoking. eHealthMe is studying from 89,889 Chantix users. Check the latest studies of Chantix.

On Jul, 16, 2026

35 people who take Oxycodone hydrochloride and Chantix together, and have interactions are studied.

Oxycodone hydrochloride and Chantix drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Chantix, by gender? *:

female:

Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypertension (high blood pressure)
Influenza
Pneumonia
Drug ineffective
Headache (pain in head)
Tinnitus (a ringing in the ears)
Abdominal pain upper
Chest discomfort

male:

Chronic kidney disease
Anxiety
Hypervolaemia (abnormally increased volume of blood)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Abscess (pus)
Acidosis (build-up of carbon dioxide in the blood)
Actinomycotic skin infection (infectious and inflammatory diseases affect the skin and the oral mucosa)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)

What are the common drug interactions of Oxycodone Hydrochloride and Chantix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Activities of daily living impaired
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

Chest discomfort
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hypersensitivity
Lip swelling
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Swelling face
Arthralgia (joint pain)
Bell's palsy (facial paralysis)

50-59:

Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Bone density decreased
Constipation
Crying
Emotional distress
Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Chest pain
Cellulitis (infection under the skin)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Anxiety
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Arthralgia (joint pain)
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 14.29%
Immunodeficiency Common Variable: 4 people, 11.43%
Muscle Spasms (muscle contraction): 3 people, 8.57%
Infection: 3 people, 8.57%
Hiv Infection: 3 people, 8.57%
Colon Cancer: 3 people, 8.57%
Stress And Anxiety: 2 people, 5.71%
Renal Cell Carcinoma (a kidney cancer): 2 people, 5.71%
Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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