Oxycodone hydrochloride and Elmiron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Elmiron (pentosan polysulfate sodium). Common drug interactions include retinal pigmentation among females.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Elmiron. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Elmiron?

Elmiron has active ingredients of pentosan polysulfate sodium. It is often used in interstitial cystitis (ic). eHealthMe is studying from 10,215 Elmiron users. Check the latest studies of Elmiron.



On Aug, 12, 2026

18 people who take Oxycodone hydrochloride and Elmiron together, and have interactions are studied.

Oxycodone hydrochloride and Elmiron drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Elmiron, by gender? *:

female:

  1. Retinal pigmentation (pigmentation of retina)
  2. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
  3. Arthralgia (joint pain)
  4. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  5. Myalgia (muscle pain)
  6. Renal disorder (kidney disease)
  7. Abdominal distension
  8. Abdominal pain
  9. Bell's palsy (facial paralysis)
  10. Genital herpes (herpes infection of genital)

male:

n/a

What are the common drug interactions of Oxycodone Hydrochloride and Elmiron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Viral infection

20-29:

n/a

30-39:

n/a

40-49:

  1. Retinal pigmentation (pigmentation of retina)
  2. Bell's palsy (facial paralysis)
  3. Genital herpes (herpes infection of genital)
  4. Hypertension (high blood pressure)
  5. Nerve block (the interruption of signals travelling along a nerve)

50-59:

  1. Retinal pigmentation (pigmentation of retina)
  2. Headache (pain in head)
  3. Retinopathy (acute damage to the retina of the eye)
  4. Vitreous degeneration (serious vision problems in humans)
  5. Age-related macular degeneration
  6. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
  7. Renal disorder (kidney disease)
  8. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

60+:

  1. Retinal pigmentation (pigmentation of retina)
  2. Arthralgia (joint pain)
  3. Mucous stools (mucous with stool)
  4. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  5. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  6. Myalgia (muscle pain)
  7. Abdominal distension
  8. Abdominal pain
  9. Infrequent bowel movements
  10. Loss of consciousness

What are the existing conditions these people have? *

  1. Cystitis Interstitial (unknown cause characterized by bladder pain): 9 people, 50.00%
  2. High Blood Pressure: 4 people, 22.22%
  3. Thyroid Diseases: 4 people, 22.22%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 22.22%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
  6. Stress And Anxiety: 3 people, 16.67%
  7. Indigestion: 3 people, 16.67%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 16.67%
  9. Migraine (headache): 3 people, 16.67%
  10. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone hydrochloride and Elmiron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone hydrochloride and Elmiron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Elmiron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Elmiron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and pentosan polysulfate sodium (the active ingredients of Oxycodone hydrochloride and Elmiron, respectively), and Oxycodone hydrochloride and Elmiron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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