Oxycodone hydrochloride and Janumet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Janumet (metformin hydrochloride; sitagliptin phosphate). Common drug interactions include salivary hypersecretion among females and gastroenteritis escherichia coli among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Janumet. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

On Jul, 16, 2026

31 people who take Oxycodone hydrochloride and Janumet together, and have interactions are studied.

Oxycodone hydrochloride and Janumet drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Janumet, by gender? *:

female:

Salivary hypersecretion (excess saliva secretion)
Stomatitis (inflammation of mucous membrane of mouth)
Asthenia (weakness)
Death
Hospitalisation
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Abdominal pain
Epigastric discomfort
Hypophagia (reduced food intake)
Nausea (feeling of having an urge to vomit)

male:

Gastroenteritis escherichia coli (inflammation of stomach and intestine caused by escherichia coli infection)
Colitis (inflammation of colon)
Burns third degree
Cardiomegaly (increased size of heart than normal)
Decreased appetite
Dysphonia (speech disorder attributable to a disorder of phonation)
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Heart valve incompetence (heart's valves do not work correctly)
Infection

What are the common drug interactions of Oxycodone Hydrochloride and Janumet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Infection
Pneumonia

50-59:

n/a

60+:

Gastroenteritis escherichia coli (inflammation of stomach and intestine caused by escherichia coli infection)
Salivary hypersecretion (excess saliva secretion)
Decreased appetite
Abdominal pain
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Confusional state
Epigastric discomfort
Fall
Hypophagia (reduced food intake)
Pulmonary oedema (fluid accumulation in the lungs)

What are the existing conditions these people have? *

Bronchial Carcinoma (lung cancer): 6 people, 19.35%
Adenocarcinoma Pancreas (cancer of pancreas): 5 people, 16.13%
Type 2 Diabetes: 3 people, 9.68%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.68%
Endocarditis (inflammation in heart muscle): 3 people, 9.68%
Dyslipidaemia (abnormal amount of lipids): 3 people, 9.68%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 9.68%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.45%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 6.45%
High Blood Pressure: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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