Oxycodone hydrochloride and Thiamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Thiamine (thiamine (vitamin b1)). Common drug interactions include general physical health deterioration among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Thiamine. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

33 people who take Oxycodone hydrochloride and Thiamine together, and have interactions are studied.

Oxycodone hydrochloride and Thiamine drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Thiamine, by gender? *:

female:

General physical health deterioration (weak health status)
Hand deformity
Headache (pain in head)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hepatic enzyme increased
Hepatitis (inflammation of the liver)
Hip fracture
Hypersensitivity
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)

male:

Pyrexia (fever)
Arthralgia (joint pain)
Enterococcal sepsis
Febrile neutropenia (fever with reduced white blood cells)
Hepatotoxicity (chemical-driven liver damage)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Anaemia macrocytic (a macrocytic class of anaemia)
Anxiety
Blood creatine phosphokinase increased

What are the common drug interactions of Oxycodone Hydrochloride and Thiamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Bacterial sepsis
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Enterococcal sepsis
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

20-29:

n/a

30-39:

Anxiety
Arthralgia (joint pain)
Depression
Emotional distress
Fracture
Fractured sacrum
Gait disturbance
Hip fracture
Joint dislocation (a joint position is changed from normal position)
Joint injury

40-49:

Injection site reaction
Injury
Irritable bowel syndrome
Joint swelling
Lower respiratory tract infection
Malignant neoplasm progression (cancer tumour came back)
Maternal exposure during pregnancy (use of substance during pregnancy)
Mobility decreased (ability to move is reduced)
Muscle injury
Muscular weakness (muscle weakness)

50-59:

n/a

60+:

Pyrexia (fever)
Salmonella bacteraemia (infection of blood by salmonella bacteria)
Hepatotoxicity (chemical-driven liver damage)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pain in extremity
Pulmonary mass
Anaemia macrocytic (a macrocytic class of anaemia)
Blood creatine phosphokinase increased
Blood urea increased
Cold sweat

What are the existing conditions these people have? *

Constipation: 9 people, 27.27%
Insomnia (sleeplessness): 7 people, 21.21%
Asthma: 7 people, 21.21%
Fever: 6 people, 18.18%
Hypokalemia (low potassium): 5 people, 15.15%
Depression: 5 people, 15.15%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 12.12%
Stress And Anxiety: 4 people, 12.12%
Anaemia (lack of blood): 3 people, 9.09%
Stomatitis (inflammation of mucous membrane of mouth): 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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