Oxycodone hydrochloride and Truvada drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Truvada (emtricitabine; tenofovir disoproxil fumarate). Common drug interactions include emotional distress among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Truvada. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

On Jul, 19, 2026

22 people who take Oxycodone hydrochloride and Truvada together, and have interactions are studied.

Oxycodone hydrochloride and Truvada drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Truvada, by gender? *:

female:

Emotional distress
Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic kidney disease
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal impairment (severely reduced kidney function)
Osteoporosis (bones weak and more likely to break)
Tooth loss
Kidney infection
Nephrolithiasis (calculi in the kidneys)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Renal failure (kidney dysfunction)
Decreased activity
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Nephropathy (damage to or disease of a kidney)
Bone loss
Bone disorder
Death
Fatigue (feeling of tiredness)

What are the common drug interactions of Oxycodone Hydrochloride and Truvada, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Emotional distress
Death
Decreased activity
Fear
Impaired work ability
Quality of life decreased
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Skeletal injury (bone and supporting muscle injury)
Bone density decreased

30-39:

Anxiety
Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic kidney disease
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal impairment (severely reduced kidney function)
Depression
Nephropathy (damage to or disease of a kidney)
Renal failure (kidney dysfunction)
Arthralgia (joint pain)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Bone density decreased
Chronic kidney disease
Fatigue (feeling of tiredness)
Hip fracture
Multiple fractures
Nephrolithiasis (calculi in the kidneys)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Bone density decreased
Bone loss
Multiple fractures
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)
Renal injury (kidney injury)

60+:

Emotional distress
Chronic kidney disease
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Dysstasia (difficulty in standing)
Bone density decreased
Foot fracture
Hip fracture
Osteopenia (a condition where bone mineral density is lower than normal)
Tooth loss
Bone disorder

What are the existing conditions these people have? *

Depression: 7 people, 31.82%
High Blood Pressure: 6 people, 27.27%
Hypersensitivity: 6 people, 27.27%
Bacterial Infection: 5 people, 22.73%
Fungal Infection: 5 people, 22.73%
Viral Infection: 4 people, 18.18%
High Blood Cholesterol: 4 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 18.18%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 4 people, 18.18%
Nausea (feeling of having an urge to vomit): 4 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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