Oxycodone and Durezol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Durezol (difluprednate). Common drug interactions include anxiety among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Durezol. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Durezol?

Durezol has active ingredients of difluprednate. It is often used in uveitis. eHealthMe is studying from 3,441 Durezol users. Check the latest studies of Durezol.



On Jul, 16, 2026

74 people who take Oxycodone and Durezol together, and have interactions are studied.

Oxycodone and Durezol drug interactions.

What are the common drug interactions of Oxycodone and Durezol, by gender? *:

female:

  1. Anxiety
  2. Death
  3. Depression
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Pneumonia
  8. Renal failure (kidney dysfunction)
  9. Urinary tract infection
  10. Vitreous haemorrhage (intraocular (inside the eye) bleeding)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Blindness
  4. Bone density decreased
  5. Cellulitis (infection under the skin)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Depression
  8. Emotional distress
  9. Neck pain
  10. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

What are the common drug interactions of Oxycodone and Durezol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Diarrhoea haemorrhagic (bloody diarrhoea)

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Cataract (clouding of the lens inside the eye)
  4. Coccydynia (pain in the coccyx or tailbone area)
  5. Influenza like illness
  6. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Pyrexia (fever)
  9. Visual impairment
  10. Injection site pain

50-59:

  1. Chronic kidney disease
  2. Abscess limb (limb infection)
  3. Cellulitis (infection under the skin)
  4. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  5. Nerve injury
  6. Scar
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Septic shock (shock due to blood infection)
  9. Streptococcal sepsis (whole body inflammation by streptococcal)
  10. Bone pain

60+:

  1. Memory impairment
  2. Disturbance in attention
  3. Diarrhoea
  4. Pyrexia (fever)
  5. Activities of daily living impaired
  6. Death
  7. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Renal injury (kidney injury)
  10. Swelling

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 16.22%
  2. High Blood Pressure: 12 people, 16.22%
  3. Multiple Myeloma (cancer of the plasma cells): 11 people, 14.86%
  4. High Blood Cholesterol: 11 people, 14.86%
  5. Stress And Anxiety: 8 people, 10.81%
  6. Nausea (feeling of having an urge to vomit): 7 people, 9.46%
  7. Infection: 7 people, 9.46%
  8. Diabetes: 6 people, 8.11%
  9. Muscle Spasms (muscle contraction): 6 people, 8.11%
  10. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 6 people, 8.11%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and Durezol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and Durezol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Durezol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Durezol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and difluprednate (the active ingredients of Oxycodone and Durezol, respectively), and Oxycodone and Durezol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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