Oxycodone and Isradipine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Isradipine (isradipine). Common drug interactions include pyrexia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Isradipine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Isradipine?

Isradipine has active ingredients of isradipine. It is often used in high blood pressure. eHealthMe is studying from 727 Isradipine users. Check the latest studies of Isradipine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

17 people who take Oxycodone and Isradipine together, and have interactions are studied.

Oxycodone and Isradipine drug interactions.

What are the common drug interactions of Oxycodone and Isradipine, by gender? *:

female:

Pyrexia (fever)
Neutropenia (an abnormally low number of neutrophils)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Malignant neoplasm progression (cancer tumour came back)
Paraneoplastic syndrome (symptom that is the consequence of the presence of cancer in the body)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Enterovirus infection
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased

male:

Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Rectal haemorrhage (bleeding from anus)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal bacteraemia (a bacterial infection of blood)
Weight decreased
Bacteraemia (presence of bacteria in the blood)

What are the common drug interactions of Oxycodone and Isradipine, by age (0-1 to 60+)? *:

0-1:

Extravasation (leakage of a fluid)
Infusion site pain
Infusion site swelling

2-9:

Pyrexia (fever)
Neutropenia (an abnormally low number of neutrophils)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Leukaemia recurrent (repeat cancer of bone marrow or blood cells)

10-19:

Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Malignant neoplasm progression (cancer tumour came back)
Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Paraneoplastic syndrome (symptom that is the consequence of the presence of cancer in the body)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Enterovirus infection
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased

20-29:

Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Diarrhoea
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Staphylococcal bacteraemia (a bacterial infection of blood)

30-39:

n/a

40-49:

Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Adenovirus infection
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Graft versus host disease in liver (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the liver)
Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
Lactic acidosis (low ph in body tissues)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Septic shock (shock due to blood infection)
Ascites (accumulation of fluid in the abdominal cavity)

50-59:

n/a

60+:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Bacteraemia (presence of bacteria in the blood)
Dyspnoea (difficult or laboured respiration)
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Constipation: 7 people, 41.18%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 7 people, 41.18%
Viral Infection: 6 people, 35.29%
Flatulence (flatus expelled through the anus): 6 people, 35.29%
Bacterial Infection: 6 people, 35.29%
Lip Dry: 6 people, 35.29%
Neuralgia (pain in one or more nerves): 6 people, 35.29%
Sleep Disorder: 6 people, 35.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 35.29%
Fungal Infection: 6 people, 35.29%

* Approximation only. Some reports may have incomplete information.

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