Ofev and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ofev (nintedanib esylate) and Oxycodone (oxycodone hydrochloride). Common drug interactions include productive cough among females and loss of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Ofev and Oxycodone. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Ofev?

Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,789 Ofev users. Check the latest studies of Ofev.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,583 Oxycodone users. Check the latest studies of Oxycodone.



On Oct, 22, 2025

76 people who take Ofev and Oxycodone together, and have interactions are studied.

Ofev and Oxycodone drug interactions.

What are the common drug interactions of Ofev and Oxycodone, by gender? *:

female:

  1. Productive cough
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Sinusitis (inflammation of sinus)
  4. Urinary tract infection
  5. Dizziness
  6. Abdominal pain
  7. Alopecia (absence of hair from areas of the body)
  8. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  9. Asthenia (weakness)
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

  1. Loss of consciousness
  2. Overdose
  3. Nausea (feeling of having an urge to vomit)
  4. Dyspnoea (difficult or laboured respiration)
  5. Headache (pain in head)
  6. Cough
  7. Dyspnoea at rest (difficult or laboured breathing during rest)
  8. Chest pain
  9. Constipation
  10. Dizziness

What are the common drug interactions of Ofev and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Confusional state
  4. Diarrhoea
  5. Nausea (feeling of having an urge to vomit)
  6. Vomiting
  7. Arthralgia (joint pain)
  8. Cystic fibrosis (disease of the secretary glands)
  9. Fatigue (feeling of tiredness)
  10. Joint stiffness

50-59:

  1. Fall
  2. Haematuria (presence of blood in urine)
  3. Lung neoplasm malignant (cancer tumour of lung)
  4. Anxiety
  5. Chest discomfort
  6. Chest pain
  7. Fatigue (feeling of tiredness)
  8. Headache (pain in head)
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  10. Nausea (feeling of having an urge to vomit)

60+:

  1. Loss of consciousness
  2. Overdose
  3. Dyspnoea (difficult or laboured respiration)
  4. Fatigue (feeling of tiredness)
  5. Nausea (feeling of having an urge to vomit)
  6. Cough
  7. Chest pain
  8. Constipation
  9. Decreased appetite
  10. Influenza

What are the existing conditions these people have? *

  1. Idiopathic Pulmonary Fibrosis (chronic lung disease): 63 people, 82.89%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 11.84%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 7.89%
  4. High Blood Pressure: 6 people, 7.89%
  5. High Blood Cholesterol: 6 people, 7.89%
  6. Interstitial Lung Disease: 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Ofev and Oxycodone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ofev and Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ofev:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ofev and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nintedanib esylate and oxycodone hydrochloride (the active ingredients of Ofev and Oxycodone, respectively), and Ofev and Oxycodone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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