Oxycodone and Remifentanil hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Remifentanil hydrochloride (remifentanil hydrochloride). Common drug interactions include disseminated intravascular coagulation among females and hyperkalaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Remifentanil hydrochloride. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Remifentanil hydrochloride?

Remifentanil hydrochloride has active ingredients of remifentanil hydrochloride. eHealthMe is studying from 1,327 Remifentanil hydrochloride users. Check the latest studies of Remifentanil hydrochloride.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

11 people who take Oxycodone and Remifentanil hydrochloride together, and have interactions are studied.

Oxycodone and Remifentanil hydrochloride drug interactions.

What are the common drug interactions of Oxycodone and Remifentanil Hydrochloride, by gender? *:

female:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Adenomyosis (presence of ectopic glandular tissue found in muscle)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Gastric cancer (stomach cancer)
Hepatocellular injury (liver injury)
Depressed level of consciousness

male:

Hyperkalaemia (damage to or disease of the kidney)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Anaphylactic reaction (serious allergic reaction)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Hepatocellular injury (liver injury)
Hypotension (abnormally low blood pressure)
Lip swelling
Swollen tongue (swelling of tongue)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the common drug interactions of Oxycodone and Remifentanil Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Depressed level of consciousness
Dyskinesia (abnormality or impairment of voluntary movement)
Muscle spasms (muscle contraction)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Unresponsive to stimuli

30-39:

n/a

40-49:

n/a

50-59:

Adenomyosis (presence of ectopic glandular tissue found in muscle)
Gastric cancer (stomach cancer)

60+:

Hyperkalaemia (damage to or disease of the kidney)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Interstitial lung disease
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Coagulopathy (blood's ability to clot is impaired)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Hepatocellular injury (liver injury)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the existing conditions these people have? *

Heart Attack: 3 people, 27.27%
White Blood Cell Count Decreased: 1 person, 9.09%
Tumor Pain: 1 person, 9.09%
Anaesthesia: 1 person, 9.09%
Arrhythmias (irregular heartbeat): 1 person, 9.09%
Aspartate Aminotransferase Increased: 1 person, 9.09%
Blood Glucose Decreased: 1 person, 9.09%
Colon Cancer: 1 person, 9.09%
Constipation: 1 person, 9.09%
Cough: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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