Oxycodone and Takhzyro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Takhzyro (lanadelumab-flyo). Common drug interactions include hereditary angioedema among females and hereditary angioedema among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Takhzyro. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Takhzyro?

Takhzyro has active ingredients of lanadelumab-flyo. eHealthMe is studying from 2,828 Takhzyro users. Check the latest studies of Takhzyro.



On Jul, 16, 2026

38 people who take Oxycodone and Takhzyro together, and have interactions are studied.

Oxycodone and Takhzyro drug interactions.

What are the common drug interactions of Oxycodone and Takhzyro, by gender? *:

female:

  1. Hereditary angioedema (recurrent episodes of severe swelling)
  2. Drug ineffective
  3. Gastric haemorrhage (bleeding stomach)
  4. Laryngeal oedema (swelling of larynx)
  5. Stress
  6. Tooth infection
  7. Asthenia (weakness)
  8. Dizziness
  9. Fatigue (feeling of tiredness)
  10. Headache (pain in head)

male:

  1. Hereditary angioedema (recurrent episodes of severe swelling)
  2. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  3. Adverse drug reaction
  4. Pneumonia
  5. Injection site discharge
  6. Injection site pain
  7. Lung carcinoma cell type unspecified stage iv (the lung cancer has spread to other organs of the body, such as the other lung, brain, or liver)
  8. Rhinorrhoea (watery mucus discharge from the nose)
  9. Pulmonary thrombosis (scarring in the lungs)
  10. Prostatomegaly (enlargement of the prostate)

What are the common drug interactions of Oxycodone and Takhzyro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hereditary angioedema (recurrent episodes of severe swelling)
  2. Laryngeal oedema (swelling of larynx)
  3. Stress
  4. Tooth infection
  5. Temperature intolerance (inability to go in temperature)

30-39:

n/a

40-49:

n/a

50-59:

  1. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  2. Hereditary angioedema (recurrent episodes of severe swelling)
  3. Pulmonary thrombosis (scarring in the lungs)
  4. Prostatomegaly (enlargement of the prostate)
  5. Urinary tract infection
  6. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  7. Fatigue (feeling of tiredness)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Nausea (feeling of having an urge to vomit)

60+:

  1. Asthenia (weakness)
  2. Dizziness
  3. Pruritus (severe itching of the skin)
  4. Drug ineffective
  5. Fatigue (feeling of tiredness)
  6. Gastric haemorrhage (bleeding stomach)
  7. Headache (pain in head)
  8. Hereditary angioedema (recurrent episodes of severe swelling)
  9. Thrombosis (formation of a blood clot inside a blood vessel)
  10. Vision blurred

What are the existing conditions these people have? *

  1. Hereditary Angioedema (recurrent episodes of severe swelling): 26 people, 68.42%
  2. Immune System Disorder: 15 people, 39.47%
  3. Nausea (feeling of having an urge to vomit): 9 people, 23.68%
  4. Hyperemesis Gravidarum (a condition characterized by severe nausea, vomiting, weight loss, and electrolyte disturbance): 5 people, 13.16%
  5. Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and Takhzyro?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and Takhzyro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Takhzyro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Takhzyro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and lanadelumab-flyo (the active ingredients of Oxycodone and Takhzyro, respectively), and Oxycodone and Takhzyro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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