Oxycodone and Ticagrelor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Ticagrelor (ticagrelor). Common drug interactions include atrial flutter among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Ticagrelor. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Ticagrelor?

Ticagrelor has active ingredients of ticagrelor. eHealthMe is studying from 8,499 Ticagrelor users. Check the latest studies of Ticagrelor.



On Aug, 08, 2026

68 people who take Oxycodone and Ticagrelor together, and have interactions are studied.

Oxycodone and Ticagrelor drug interactions.

What are the common drug interactions of Oxycodone and Ticagrelor, by gender? *:

female:

  1. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  2. Syncope (loss of consciousness with an inability to maintain postural tone)
  3. Presyncope
  4. Oral mucosal blistering (mouth ulcer)
  5. Pruritus (severe itching of the skin)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Swollen tongue (swelling of tongue)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Acquired haemophilia (bleeding disorder disease)
  10. Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)

male:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  3. Acute myocardial infarction (acute heart attack)
  4. Gastrointestinal ulcer
  5. Infection
  6. Angina pectoris (chest pain due to ischemia of the heart muscle)
  7. Blood pressure decreased
  8. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  9. Coma (state of unconsciousness lasting more than six hours)
  10. Diabetes mellitus inadequate control

What are the common drug interactions of Oxycodone and Ticagrelor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  3. Walking disability
  4. Chest pain
  5. Pain in extremity
  6. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
  10. Cold sweat

50-59:

  1. Acute myocardial infarction (acute heart attack)
  2. Coma (state of unconsciousness lasting more than six hours)
  3. Constipation
  4. Leukopenia (less number of white blood cells in blood)
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Neutropenia (an abnormally low number of neutrophils)
  7. Overdose
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Urinary retention (the inability to completely or partially empty the bladder)
  10. Alopecia (absence of hair from areas of the body)

60+:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Gastrointestinal ulcer
  4. Infection
  5. Oral mucosal blistering (mouth ulcer)
  6. Pruritus (severe itching of the skin)
  7. Swollen tongue (swelling of tongue)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Acquired haemophilia (bleeding disorder disease)

What are the existing conditions these people have? *

  1. High Blood Pressure: 10 people, 14.71%
  2. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 8 people, 11.76%
  3. Constipation: 7 people, 10.29%
  4. Psoriasis (immune-mediated disease that affects the skin): 7 people, 10.29%
  5. Depression: 7 people, 10.29%
  6. Heart Attack: 7 people, 10.29%
  7. Muscle Spasms (muscle contraction): 7 people, 10.29%
  8. Enlarged Prostate: 7 people, 10.29%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 10.29%
  10. Hyperkalemia (damage to or disease of the kidney): 6 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and Ticagrelor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ticagrelor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ticagrelor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and ticagrelor (the active ingredients of Oxycodone and Ticagrelor, respectively), and Oxycodone and Ticagrelor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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