Oxycodone and Trusopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Trusopt (dorzolamide hydrochloride). Common drug interactions include aortic valve stenosis among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Trusopt. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 3,165 Trusopt users. Check the latest studies of Trusopt.

On Jul, 24, 2026

40 people who take Oxycodone and Trusopt together, and have interactions are studied.

Oxycodone and Trusopt drug interactions.

What are the common drug interactions of Oxycodone and Trusopt, by gender? *:

female:

Aortic valve stenosis (narrowing of the aortic valve)
Bladder mass
Bone disorder
Brain natriuretic peptide increased
Cardiomegaly (increased size of heart than normal)
Chest pain
Dyspnoea (difficult or laboured respiration)
Fall
Gastroenteritis radiation (radiation induced inflammation of stomach and intestine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Haematochezia (passage of stools containing blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Ankle fracture
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthropathy
Blood immunoglobulin g increased
Cardiac asthma (wheezing, coughing or shortness of breath due to congestive heart failure)

What are the common drug interactions of Oxycodone and Trusopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Lung infection
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Rash
Renal failure (kidney dysfunction)
Respiratory tract infection
Thrombosis (formation of a blood clot inside a blood vessel)
Upper respiratory tract infection
Weight increased

50-59:

Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)

60+:

Anxiety
Bone disorder
Diarrhoea
Injury
Tooth extraction
Cardiac failure congestive
Dyspnoea exertional (breathlessness or shortness of breath)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Osteomyelitis (infection of bone)
Pleural effusion (water on the lungs)

What are the existing conditions these people have? *

Depression: 11 people, 27.50%
Breast Cancer: 7 people, 17.50%
Breast Cancer Metastatic: 7 people, 17.50%
Multiple Myeloma (cancer of the plasma cells): 7 people, 17.50%
Cardiac Failure Congestive: 6 people, 15.00%
High Blood Pressure: 6 people, 15.00%
Arrhythmias (irregular heartbeat): 5 people, 12.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 12.50%
Stable Angina (a constant chest pain): 5 people, 12.50%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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