Oxycodone and Urocit-k drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Urocit-k (potassium citrate). Common drug interactions include hypotension among females and blood cholesterol increased among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Urocit-k. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Urocit-k?

Urocit-k has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 708 Urocit-k users. Check the latest studies of Urocit-k.



On Jul, 12, 2026

20 people who take Oxycodone and Urocit-k together, and have interactions are studied.

Oxycodone and Urocit-k drug interactions.

What are the common drug interactions of Oxycodone and Urocit-K, by gender? *:

female:

  1. Hypotension (abnormally low blood pressure)
  2. Lung disorder (lung disease)
  3. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  4. Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)
  5. Osteonecrosis of jaw (death of bone of jaw)
  6. Renal failure (kidney dysfunction)
  7. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
  8. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  9. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  10. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

male:

  1. Blood cholesterol increased
  2. Drug ineffective
  3. Abdominal pain
  4. Adhesion
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Blindness
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  8. Dehydration (dryness resulting from the removal of water)
  9. Fall
  10. Hypocalcaemia (levels of calcium in blood serum are abnormally low)

What are the common drug interactions of Oxycodone and Urocit-K, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blood potassium decreased
  2. Blood prolactin increased
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Drug level decreased
  5. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Vision blurred
  8. Vomiting

30-39:

n/a

40-49:

  1. Diarrhoea
  2. Fatigue (feeling of tiredness)
  3. Actinic keratosis (skin disease due to sun exposure)
  4. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  5. Anaemia macrocytic (a macrocytic class of anaemia)
  6. Anaemia of malignant disease
  7. Arteriosclerosis (thickening and hardening of arteries)
  8. Arthralgia (joint pain)
  9. Asthenia (weakness)
  10. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)

50-59:

  1. Bullous lung disease
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  4. Decreased appetite
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Diarrhoea
  7. Duodenal polyp (duodenal epithelial tumours)
  8. Erythema (redness of the skin)
  9. Fatigue (feeling of tiredness)
  10. Gait disturbance

60+:

  1. Blood cholesterol increased
  2. Drug ineffective
  3. Abdominal pain
  4. Adhesion
  5. Arthralgia (joint pain)
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Blindness
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Dehydration (dryness resulting from the removal of water)
  10. Dizziness

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 7 people, 35.00%
  2. Bone Loss: 5 people, 25.00%
  3. Insomnia (sleeplessness): 4 people, 20.00%
  4. Nausea (feeling of having an urge to vomit): 3 people, 15.00%
  5. High Blood Cholesterol: 3 people, 15.00%
  6. Hypersensitivity: 3 people, 15.00%
  7. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 3 people, 15.00%
  8. High Blood Pressure: 2 people, 10.00%
  9. Indigestion: 2 people, 10.00%
  10. Influenza Like Illness: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and Urocit-k?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and Urocit-k:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Urocit-k:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Urocit-k and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and potassium citrate (the active ingredients of Oxycodone and Urocit-k, respectively), and Oxycodone and Urocit-k (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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