Oxycodone and Xenazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Xenazine (tetrabenazine). Common drug interactions include tremor among females and convulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Xenazine. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,588 Oxycodone users. Check the latest studies of Oxycodone.

What is Xenazine?

Xenazine has active ingredients of tetrabenazine. eHealthMe is studying from 7,308 Xenazine users. Check the latest studies of Xenazine.



On Nov, 04, 2025

28 people who take Oxycodone and Xenazine together, and have interactions are studied.

Oxycodone and Xenazine drug interactions.

What are the common drug interactions of Oxycodone and Xenazine, by gender? *:

female:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  3. Urinary tract infection
  4. Vaginal prolapse (portion of the vaginal canal protruding (prolapsing) from the opening of the vagina)
  5. Vertebral foraminal stenosis (narrowing of the intervertebral foramen)
  6. Visual impairment
  7. Weight increased
  8. Confusional state
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

male:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Hospitalisation
  4. Abdominal distension
  5. Abnormal behaviour
  6. Aggression
  7. Chorea (abnormal involuntary movement disorder)
  8. Death
  9. Dyskinesia (abnormality or impairment of voluntary movement)
  10. Dystonia (abnormal muscle tone)

What are the common drug interactions of Oxycodone and Xenazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal distension
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Dystonia (abnormal muscle tone)
  4. Ileus (a painful obstruction of the ileum or other part of the intestine)
  5. Pneumonia
  6. Upper respiratory tract infection
  7. Urinary retention (the inability to completely or partially empty the bladder)
  8. Viral infection
  9. White blood cell count increased

20-29:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

30-39:

n/a

40-49:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
  3. Arthralgia (joint pain)
  4. Fatigue (feeling of tiredness)
  5. Abnormal behaviour
  6. Aggression
  7. Chorea (abnormal involuntary movement disorder)
  8. Diarrhoea
  9. Dyskinesia (abnormality or impairment of voluntary movement)
  10. Feeding disorder (when children refuse to eat certain food groups)

50-59:

n/a

60+:

  1. Confusional state
  2. Drug ineffective
  3. Agitation (state of anxiety or nervous excitement)
  4. Arthralgia (joint pain)
  5. Asthenia (weakness)
  6. Chest pain
  7. Constipation
  8. Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
  9. Death
  10. Dyskinesia (abnormality or impairment of voluntary movement)

What are the existing conditions these people have? *

  1. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 14.29%
  2. Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 3 people, 10.71%
  3. Bleeding Disorders: 3 people, 10.71%
  4. Tardive Dyskinesia (a disorder that involves involuntary movements): 2 people, 7.14%
  5. Indigestion: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and Xenazine:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xenazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xenazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and tetrabenazine (the active ingredients of Oxycodone and Xenazine, respectively), and Oxycodone and Xenazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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