Oxycontin and Dramamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycontin (oxycodone hydrochloride) and Dramamine (dimenhydrinate). Common drug interactions include pleural effusion among females and bipolar i disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycontin and Dramamine. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

What is Dramamine?

Dramamine has active ingredients of dimenhydrinate. It is often used in motion sickness. eHealthMe is studying from 1,386 Dramamine users. Check the latest studies of Dramamine.

On Jul, 03, 2026

28 people who take Oxycontin and Dramamine together, and have interactions are studied.

Oxycontin and Dramamine drug interactions.

What are the common drug interactions of Oxycontin and Dramamine, by gender? *:

female:

Pleural effusion (water on the lungs)
Pneumonia
Stomatitis (inflammation of mucous membrane of mouth)
Vomiting
Memory impairment
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Dry eye (lack of adequate tears)
Dry mouth

male:

Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Blindness transient (sudden loss of vision)
Euphoric mood (excessively happy but may become angry or irritable)
Feeling jittery
Hangover
Loss of consciousness
Malignant neoplasm progression (cancer tumour came back)
Mania (a state of abnormally elevated or irritable mood)
Mobility decreased (ability to move is reduced)
Muscle spasms (muscle contraction)

What are the common drug interactions of Oxycontin and Dramamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Completed suicide (act of taking one's own life)
Drug dependence
Hospitalisation
Increased appetite
Overdose
Substance abuse

40-49:

n/a

50-59:

Oropharyngeal blistering (blister of oropharynx)
Fall
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Blindness transient (sudden loss of vision)
Blood pressure decreased
Burning sensation
Cardiovascular disorder (heart diseases)
Decreased appetite
Depression
Drug intolerance (drug sensitivity)

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Fall
Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Oral pain
Pain in extremity
Pleural effusion (water on the lungs)
Vomiting
Malignant neoplasm progression (cancer tumour came back)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 25.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 25.00%
Insomnia (sleeplessness): 5 people, 17.86%
Type 2 Diabetes: 4 people, 14.29%
High Blood Pressure: 3 people, 10.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.14%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 7.14%
Hypomania (a mild form of mania, marked by elation and hyperactivity): 2 people, 7.14%
Bipolar Disorder (mood disorder): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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